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Disease Myelinolysis, Central Pontine

Name Myelinolysis, Central Pontine
Synonyms Central Pontine Myelinoclasis | Central Pontine Myelinolysis | Extrapontine Myelinoclases | Extrapontine Myelinoclasis | Extrapontine Myelinolyses | Extrapontine Myelinolysis | Myelinoclases, Extrapontine | Myelinoclasis, Central Pontine | Myelinoclasis, Extrapontine | Myelinolyses, Extrapontine | Myelinolysis, Extrapontine | Pontine Myelinolysis, Central
Definition A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Categories Metabolic disease | Nervous system disease
MeSH® ID D017590
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1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases, Metabolic Has associated chemicals Has associated genes Myelinolysis, Central Pontine Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Demyelinating Diseases Has associated chemicals Has associated genes Has associated exposure references Myelinolysis, Central Pontine Has associated chemicals Has associated genes
3. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases, Metabolic Has associated chemicals Has associated genes Myelinolysis, Central Pontine Has associated chemicals Has associated genes

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None.