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Disease Endodermal Sinus Tumor

Name Endodermal Sinus Tumor
Synonyms Endodermal Sinus Tumors | Tumor, Endodermal Sinus | Tumors, Endodermal Sinus | Tumors, Yolk Sac | Tumor, Yolk Sac | Yolk Sac Tumor | Yolk Sac Tumors
Definition An unusual and aggressive tumor of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumor found in children. It is characterized by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (Schiller-Duval body). The tumor is rarely bilateral. Before the use of combination chemotherapy, the tumor was almost invariably fatal. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1189)
Categories Cancer
MeSH® ID D018240
External Links

Top ↑ Ancestors

DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms by Histologic Type Has associated chemicals Has associated genes Has associated exposure references Neoplasms, Germ Cell and Embryonal Has associated chemicals Has associated genes Has associated exposure references Mesonephroma Has associated chemicals Endodermal Sinus Tumor Has associated chemicals

Top ↑ Descendants

None.