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Disease Leukocyte-Adhesion Deficiency Syndrome

Name Leukocyte-Adhesion Deficiency Syndrome
Synonyms Deficiency Syndrome, Leukocyte Adhesion | Deficiency Syndrome, Leukocyte-Adhesion | Deficiency Syndromes, Leukocyte-Adhesion | Leukocyte Adhesion Deficiency Syndrome | Leukocyte-Adhesion Deficiency Syndromes | Syndrome, Leukocyte-Adhesion Deficiency | Syndromes, Leukocyte-Adhesion Deficiency
Definition Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (RECEPTORS, LEUKOCYTE-ADHESION) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterized by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection.
Categories Immune system disease
MeSH® ID D018370
External Links

Top ↑ Ancestors

DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Immunologic Deficiency Syndromes Has associated chemicals Has associated genes Leukocyte-Adhesion Deficiency Syndrome Has associated chemicals Has associated genes

Top ↑ Descendants

Leukocyte-Adhesion Deficiency Syndrome Has associated chemicals Has associated genes
  Leukocyte adhesion deficiency type 1 Has associated chemicals Has associated genes
  Leukocyte Adhesion Deficiency, Type III Has associated chemicals Has associated genes