Skip navigation

Disease Multiple Endocrine Neoplasia Type 1

Name Multiple Endocrine Neoplasia Type 1
Synonyms ENDOCRINE ADENOMATOSIS, MULTIPLE | MEA 1 | MEA I | MEN1 | MEN 1 | MEN I | Multiple Endocrine Neoplasia Type I | MULTIPLE ENDOCRINE NEOPLASIA, TYPE I | Multiple Endocrine Neoplasms Type 1 | Neoplasia, Multiple Endocrine Type 1 | Neoplasms, Multiple Endocrine Type 1 | Neoplasms, Multiple Endocrine Type I | Wermer Syndrome | WERMER SYNDROME MEN1 SOMATIC MUTATIONS, INCLUDED
Definition A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).
Categories Cancer | Endocrine system disease | Genetic disease (inborn)
MeSH® ID D018761
OMIM® ID 131100
External Links

Top ↑ Ancestors

1. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms by Site Has associated chemicals Has associated genes Has associated exposure references Endocrine Gland Neoplasms Has associated chemicals Has associated genes Has associated exposure references Multiple Endocrine Neoplasia Has associated chemicals Has associated genes Multiple Endocrine Neoplasia Type 1 Has associated chemicals Has associated genes
2. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms, Multiple Primary Has associated chemicals Has associated genes Multiple Endocrine Neoplasia Has associated chemicals Has associated genes Multiple Endocrine Neoplasia Type 1 Has associated chemicals Has associated genes
3. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplastic Syndromes, Hereditary Has associated chemicals Has associated genes Has associated exposure references Multiple Endocrine Neoplasia Has associated chemicals Has associated genes Multiple Endocrine Neoplasia Type 1 Has associated chemicals Has associated genes
4. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Neoplastic Syndromes, Hereditary Has associated chemicals Has associated genes Has associated exposure references Multiple Endocrine Neoplasia Has associated chemicals Has associated genes Multiple Endocrine Neoplasia Type 1 Has associated chemicals Has associated genes
5. DiseasesEndocrine System Diseases Has associated chemicals Has associated genes Has associated exposure references Endocrine Gland Neoplasms Has associated chemicals Has associated genes Has associated exposure references Multiple Endocrine Neoplasia Has associated chemicals Has associated genes Multiple Endocrine Neoplasia Type 1 Has associated chemicals Has associated genes

Top ↑ Descendants

None.