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Disease Aphasia, Primary Progressive

Name Aphasia, Primary Progressive
Synonyms Aphasias, Primary Progressive | Mesulam's Syndrome | Mesulam Syndrome | Primary Progressive Aphasia | Primary Progressive Aphasias | Progressive Aphasia, Primary | Progressive Aphasias, Primary | Syndrome, Mesulam | Syndrome, Mesulam's
Definition A progressive form of dementia characterized by the global loss of language abilities and initial preservation of other cognitive functions. Fluent and nonfluent subtypes have been described. Eventually a pattern of global cognitive dysfunction, similar to ALZHEIMER DISEASE, emerges. Pathologically, there are no Alzheimer or PICK DISEASE like changes, however, spongiform changes of cortical layers II and III are present in the TEMPORAL LOBE and FRONTAL LOBE. (From Brain 1998 Jan;121(Pt 1):115-26)
Categories Mental disorder | Nervous system disease | Signs and symptoms
MeSH® ID D018888

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1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Dementia Has associated chemicals Has associated genes Has associated exposure references Aphasia, Primary Progressive
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurologic Manifestations Has associated chemicals Has associated genes Has associated exposure references Neurobehavioral Manifestations Has associated chemicals Has associated genes Has associated exposure references Communication Disorders Has associated chemicals Has associated genes Has associated exposure references Language Disorders Has associated chemicals Has associated genes Speech Disorders Has associated chemicals Has associated genes Aphasia Has associated chemicals Has associated genes Aphasia, Primary Progressive
3. DiseasesPathological Conditions, Signs and Symptoms Has associated chemicals Has associated genes Has associated exposure references Signs and Symptoms Has associated chemicals Has associated genes Has associated exposure references Neurologic Manifestations Has associated chemicals Has associated genes Has associated exposure references Neurobehavioral Manifestations Has associated chemicals Has associated genes Has associated exposure references Communication Disorders Has associated chemicals Has associated genes Has associated exposure references Language Disorders Has associated chemicals Has associated genes Speech Disorders Has associated chemicals Has associated genes Aphasia Has associated chemicals Has associated genes Aphasia, Primary Progressive
4. DiseasesMental Disorders Has associated chemicals Has associated genes Has associated exposure references Neurocognitive Disorders Has associated chemicals Has associated genes Has associated exposure references Dementia Has associated chemicals Has associated genes Has associated exposure references Aphasia, Primary Progressive

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Aphasia, Primary Progressive
  Primary Progressive Nonfluent Aphasia