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Disease Multiple System Atrophy

Name Multiple System Atrophy
Synonyms Atrophies, Multisystem | Atrophies, Multisystemic | Atrophy, Multiple System | Atrophy, Multisystem | Atrophy, Multisystemic | HYPOTENSION, ORTHOSTATIC, INCLUDED | MSA1 | MSA1, SUSCEPTIBILITY TO AUTONOMIC FAILURE, PURE, INCLUDED | Multiple System Atrophies | MULTIPLE SYSTEM ATROPHY 1, SUSCEPTIBILITY TO | Multiple System Atrophy Syndrome | Multisystem Atrophies | Multisystem Atrophy | Multisystemic Atrophies | Multisystemic Atrophy
Definition A syndrome complex composed of three conditions which represent clinical variants of the same disease process: STRIATONIGRAL DEGENERATION; SHY-DRAGER SYNDROME; and the sporadic form of OLIVOPONTOCEREBELLAR ATROPHIES. Clinical features include autonomic, cerebellar, and basal ganglia dysfunction. Pathologic examination reveals atrophy of the basal ganglia, cerebellum, pons, and medulla, with prominent loss of autonomic neurons in the brain stem and spinal cord. (From Adams et al., Principles of Neurology, 6th ed, p1076; Baillieres Clin Neurol 1997 Apr;6(1):187-204; Med Clin North Am 1999 Mar;83(2):381-92)
Categories Nervous system disease
MeSH® ID D019578
OMIM® ID 146500
External Links

Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Autonomic Nervous System Diseases Has associated chemicals Has associated genes Primary Dysautonomias Has associated chemicals Has associated genes Multiple System Atrophy Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Basal Ganglia Diseases Has associated chemicals Has associated genes Has associated exposure references Multiple System Atrophy Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Movement Disorders Has associated chemicals Has associated genes Has associated exposure references Multiple System Atrophy Has associated chemicals Has associated genes
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Multiple System Atrophy Has associated chemicals Has associated genes

Top ↑ Descendants

Multiple System Atrophy Has associated chemicals Has associated genes
  Multiple system atrophy (MSA) with orthostatic hypotension
View node Olivopontocerebellar Atrophies Has associated chemicals Has associated genes
  Shy-Drager Syndrome Has associated chemicals Has associated genes
View node Striatonigral Degeneration Has associated chemicals Has associated genes