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Disease Anti-Glomerular Basement Membrane Disease

Name Anti-Glomerular Basement Membrane Disease
Synonyms Anti GBM Disease | Anti-GBM Disease | Anti Glomerular Basement Membrane Disease | Goodpasture's Syndrome | Goodpastures Syndrome | Goodpasture Syndrome | Lung Purpura with Nephritis | Syndrome, Goodpasture | Syndrome, Goodpasture's
Definition An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
Categories Immune system disease | Respiratory tract disease | Urogenital disease (female) | Urogenital disease (male)
MeSH® ID D019867
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1. DiseasesRespiratory Tract Diseases Has associated chemicals Has associated genes Has associated exposure references Lung Diseases Has associated chemicals Has associated genes Has associated exposure references Lung Diseases, Interstitial Has associated chemicals Has associated genes Has associated exposure references Anti-Glomerular Basement Membrane Disease Has associated chemicals Has associated genes
2. DiseasesMale Urogenital Diseases Has associated chemicals Has associated genes Has associated exposure references Urologic Diseases Has associated chemicals Has associated genes Has associated exposure references Kidney Diseases Has associated chemicals Has associated genes Has associated exposure references Nephritis Has associated chemicals Has associated genes Has associated exposure references Glomerulonephritis Has associated chemicals Has associated genes Anti-Glomerular Basement Membrane Disease Has associated chemicals Has associated genes
3. DiseasesFemale Urogenital Diseases and Pregnancy Complications Has associated chemicals Has associated genes Has associated exposure references Female Urogenital Diseases Has associated chemicals Has associated genes Has associated exposure references Urologic Diseases Has associated chemicals Has associated genes Has associated exposure references Kidney Diseases Has associated chemicals Has associated genes Has associated exposure references Nephritis Has associated chemicals Has associated genes Has associated exposure references Glomerulonephritis Has associated chemicals Has associated genes Anti-Glomerular Basement Membrane Disease Has associated chemicals Has associated genes
4. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases Has associated chemicals Has associated genes Has associated exposure references Anti-Glomerular Basement Membrane Disease Has associated chemicals Has associated genes

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