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Disease Hyperhomocysteinemia

Name Hyperhomocysteinemia
Synonym Hyperhomocysteinemias
Definition Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 ╬╝mol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.
Categories Genetic disease (inborn) | Metabolic disease | Nutrition disorder
MeSH® ID D020138
External Links

Top ↑ Ancestors

1. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Amino Acid Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Hyperhomocysteinemia Has associated chemicals Has associated genes Has associated exposure references
2. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Malabsorption Syndromes Has associated chemicals Has associated genes Has associated exposure references Hyperhomocysteinemia Has associated chemicals Has associated genes Has associated exposure references
3. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Amino Acid Metabolism, Inborn Errors Has associated chemicals Has associated genes Has associated exposure references Hyperhomocysteinemia Has associated chemicals Has associated genes Has associated exposure references
4. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Nutrition Disorders Has associated chemicals Has associated genes Has associated exposure references Malnutrition Has associated chemicals Has associated genes Has associated exposure references Deficiency Diseases Has associated chemicals Has associated genes Has associated exposure references Avitaminosis Has associated chemicals Has associated genes Has associated exposure references Vitamin B Deficiency Has associated chemicals Has associated genes Has associated exposure references Hyperhomocysteinemia Has associated chemicals Has associated genes Has associated exposure references

Top ↑ Descendants

Hyperhomocysteinemia Has associated chemicals Has associated genes Has associated exposure references
  Gamma-cystathionase deficiency Has associated chemicals Has associated genes
  Homocysteinemia
View node Homocystinuria Has associated chemicals Has associated genes