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Disease Paraneoplastic Cerebellar Degeneration

Name Paraneoplastic Cerebellar Degeneration
Synonyms Anti Yo Associated Paraneoplastic Cerebellar Degeneration | Anti-Yo-Associated Paraneoplastic Cerebellar Degeneration | Cerebellar Degeneration, Paraneoplastic | Cerebellar Syndrome, Paraneoplastic | Cerebellar Syndromes, Paraneoplastic | Degeneration, Paraneoplastic Cerebellar | Paraneoplastic Cerebellar Degeneration, Anti Yo Associated | Paraneoplastic Cerebellar Degeneration, Anti-Yo-Associated | Paraneoplastic Cerebellar Syndrome | Paraneoplastic Cerebellar Syndromes
Definition Cerebellar degeneration associated with a remote neoplasm. Clinical manifestations include progressive limb and GAIT ATAXIA; DYSARTHRIA; and NYSTAGMUS, PATHOLOGIC. The histologic type of the associated neoplasm is usually carcinoma or lymphoma. Pathologically the cerebellar cortex and subcortical nuclei demonstrate diffuse degenerative changes. Anti-Purkinje cell antibodies (anti-Yo) are found in the serum of approximately 50% of affected individuals. (Adams et al., Principles of Neurology, 6th ed, p686)
Categories Cancer | Nervous system disease
MeSH® ID D020362

Top ↑ Ancestors

1. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Neoplasms by Site Has associated chemicals Has associated genes Has associated exposure references Nervous System Neoplasms Has associated chemicals Has associated genes Has associated exposure references Paraneoplastic Syndromes, Nervous System Has associated chemicals Has associated genes Paraneoplastic Cerebellar Degeneration
2. DiseasesNeoplasms Has associated chemicals Has associated genes Has associated exposure references Paraneoplastic Syndromes Has associated chemicals Has associated genes Paraneoplastic Syndromes, Nervous System Has associated chemicals Has associated genes Paraneoplastic Cerebellar Degeneration
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebellar Diseases Has associated chemicals Has associated genes Paraneoplastic Cerebellar Degeneration
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Paraneoplastic Syndromes, Nervous System Has associated chemicals Has associated genes Paraneoplastic Cerebellar Degeneration

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