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Disease Myasthenia Gravis, Autoimmune, Experimental

Name Myasthenia Gravis, Autoimmune, Experimental
Synonyms Autoimmune Experimental Myasthenia Gravis | Experimental Autoimmune Myasthenia Gravis, Passive Transfer | Experimental Myasthenia | Experimental Myasthenia Gravis | Experimental Myasthenias | Myasthenia, Experimental | Myasthenia Gravis, Autoimmune Experimental | Myasthenia Gravis, Experimental | Myasthenia Gravis, Experimental Autoimmune | Myasthenias, Experimental | Passive Transfer Experimental Autoimmune Myasthenia Gravis
Definition Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
Categories Immune system disease | Nervous system disease
MeSH® ID D020720

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1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Myasthenia Gravis Has associated chemicals Has associated genes Myasthenia Gravis, Autoimmune, Experimental Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Nervous System Autoimmune Disease, Experimental Has associated chemicals Has associated genes Myasthenia Gravis, Autoimmune, Experimental Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Diseases Has associated chemicals Has associated genes Has associated exposure references Neuromuscular Junction Diseases Has associated chemicals Has associated genes Myasthenia Gravis Has associated chemicals Has associated genes Myasthenia Gravis, Autoimmune, Experimental Has associated chemicals Has associated genes
4. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Myasthenia Gravis Has associated chemicals Has associated genes Myasthenia Gravis, Autoimmune, Experimental Has associated chemicals Has associated genes
5. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases of the Nervous System Has associated chemicals Has associated genes Has associated exposure references Nervous System Autoimmune Disease, Experimental Has associated chemicals Has associated genes Myasthenia Gravis, Autoimmune, Experimental Has associated chemicals Has associated genes

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