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Disease Striatonigral Degeneration

Name Striatonigral Degeneration
Synonyms Atrophies, Striatonigral | Atrophy, Striatonigral | Degeneration, Striatonigral | Striatonigral Atrophies | Striatonigral Atrophy | Striatonigral Degenerations
Definition A sporadic neurodegenerative disease with onset in middle-age characterized clinically by Parkinsonian features (e.g., MUSCLE RIGIDITY; HYPOKINESIA; stooped posture) and HYPOTENSION. This condition is considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Pathologic features include a prominent loss of neurons in the zona compacta of the SUBSTANTIA NIGRA and PUTAMEN. (From Adams et al., Principles of Neurology, 6th ed, p1075-6)
Categories Nervous system disease
MeSH® ID D020955
External Links
DO
DOID:4751

Top ↑ Ancestors

1. Diseases ← Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references ← Autonomic Nervous System Diseases Has associated chemicals Has associated genes ← Primary Dysautonomias Has associated chemicals Has associated genes ← Multiple System Atrophy Has associated chemicals Has associated genes ← Striatonigral Degeneration Has associated chemicals Has associated genes
2. Diseases ← Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references ← Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references ← Brain Diseases Has associated chemicals Has associated genes Has associated exposure references ← Basal Ganglia Diseases Has associated chemicals Has associated genes Has associated exposure references ← Multiple System Atrophy Has associated chemicals Has associated genes ← Striatonigral Degeneration Has associated chemicals Has associated genes
3. Diseases ← Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references ← Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references ← Movement Disorders Has associated chemicals Has associated genes Has associated exposure references ← Multiple System Atrophy Has associated chemicals Has associated genes ← Striatonigral Degeneration Has associated chemicals Has associated genes
4. Diseases ← Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references ← Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references ← Multiple System Atrophy Has associated chemicals Has associated genes ← Striatonigral Degeneration Has associated chemicals Has associated genes

Top ↑ Descendants

Striatonigral Degeneration Has associated chemicals Has associated genes
  STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2 Has associated chemicals Has associated genes
  STRIATONIGRAL DEGENERATION, CHILDHOOD-ONSET Has associated chemicals Has associated genes
  Striatonigral degeneration infantile Has associated chemicals Has associated genes
  Striatonigral Degeneration, Infantile, Mitochondrial
  THIAMINE METABOLISM DYSFUNCTION SYNDROME 4 (BILATERAL STRIATAL DEGENERATION AND PROGRESSIVE POLYNEUROPATHY TYPE) Has associated chemicals Has associated genes