These are exposure studies associated with the disease and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Yang JH, et al. (2012).||National Health and Nutrition Examination Survey (NHANES)||The current study suggests that the background exposure to some organochlorine pesticides leads to vitamin D deficiency in humans.||beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | Hexachlorobenzene | nonachlor | oxychlordane||Controls for disease:Chronic Disease | Subjects with disease:Chronic Disease | Study subjects||United States||serum||25-hydroxyvitamin D | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | Hexachlorobenzene | nonachlor | oxychlordane||Details||Vitamin D Deficiency|
|2.||Tsai RJ, et al. (2014).||National Pesticide Information Center (NPIC) | Sentinel Event Notification System for Occupational Risks (SENSOR)||Notes from the Field: Acute Illness Associated with Use of Pest Strips - Seven U.S. States and Canada, 2000-2013||Dichlorvos||Subjects with disease:Acute Disease||Canada|United States||Details||Acute Disease | Gastrointestinal Diseases | Neurologic Manifestations | Respiratory Tract Diseases|
|3.||Crowe W, et al. (2015).||Multiple regression analysis identified hair mercury as a significant predictor of disease-associated damage and disease activity in systemic lupus erythematosus patients.||disease||Mercury||Subjects with disease:Lupus Erythematosus, Systemic||United Kingdom||hair | urine||Mercury||Details||Disease Progression|
|4.||Richardson JR, et al. (2014).||Elevated serum dichlorodiphenyl dichloroethylene (DDE) levels are associated with an increased risk for Alzheimer disease, and APOE4 carriers may be more susceptible (as the allele modifies an association between DDE and scores); in vitro, both DDT and DDE increase amyloid precursor protein levels, providing mechanistic plausibility for the association.||genetics||Pesticides||Controls for disease:Alzheimer Disease | Subjects with disease:Alzheimer Disease | Subjects with gene influence:APOE||United States||brain | serum||Dichlorodiphenyl Dichloroethylene||Details||Alzheimer Disease | Disease Progression|
|5.||Comhair SA, et al. (2011).||Severe Asthma Research Program (SARP)||Environmental tobacco smoke-exposure of asthmatic individuals is associated with worse lung function, higher acuity of exacerbations, more health care utilization, and greater bronchial hyperreactivity. Environmental tobacco smoke-exposure was associated with lower levels of serum SOD activity, particularly in asthmatic women of African heritage.||disease | race | sex | tobacco||Tobacco Smoke Pollution||Subjects with disease:Asthma||United States||Details||Asthma | Disease Progression | superoxide dismutase activity|
|6.||Tran TT, et al. (2015).||Thai Cohort Study (TCS)||A high proportion of cohort members, especially females, were passive smokers at home and at public transport stations; males were more exposed at workplace and recreational places; we observed a social gradient with more passive smoking in poorer people; we also observed a dose response relationship linking graded smoke exposures to chronic conditions, such as less well-being and more psychological distress.||sex | socioeconomic status | tobacco||Tobacco Smoke Pollution||Study subjects||Thailand||Details||Chronic Disease|