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Disease Optic Atrophy, Autosomal Dominant

Name Optic Atrophy, Autosomal Dominant
Synonyms Atrophies, Juvenile Optic | Atrophies, Kjer-Type Optic | Atrophy, Juvenile Optic | Atrophy, Kjer's Optic | Atrophy, Kjer-Type Optic | Autosomal Dominant Optic Atrophy | Autosomal Dominant Optic Atrophy Kjer Type | Dominant Optic Atrophies | Dominant Optic Atrophy | Juvenile Optic Atrophies | Juvenile Optic Atrophy | Kjer Optic Atrophy | Kjer's Optic Atrophy | Kjers Optic Atrophy | Kjer-Type Optic Atrophies | Kjer Type Optic Atrophy | Kjer-Type Optic Atrophy | OAK | OPA1 | Optic Atrophies, Dominant | Optic Atrophies, Juvenile | Optic Atrophies, Kjer-Type | Optic Atrophy 1 | Optic Atrophy 1s | Optic Atrophy, Dominant | Optic Atrophy, Hereditary, Autosomal Dominant | Optic Atrophy, Juvenile | Optic Atrophy, Kjer's | Optic Atrophy, Kjer Type | Optic Atrophy, Kjer-Type | Optic Atrophy Type 1
Definition Dominant optic atrophy is a hereditary optic neuropathy causing decreased visual acuity, color vision deficits, a centrocecal scotoma, and optic nerve pallor (Hum. Genet. 1998; 102: 79-86). Mutations leading to this condition have been mapped to the OPA1 gene at chromosome 3q28-q29. OPA1 codes for a dynamin-related GTPase that localizes to mitochondria.
Categories Eye disease | Genetic disease (inborn) | Metabolic disease | Nervous system disease
MeSH® ID D029241
OMIM® ID 165500

Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Cranial Nerve Diseases Has associated chemicals Has associated genes Has associated exposure references Optic Nerve Diseases Has associated chemicals Has associated genes Optic Atrophy Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes
3. DiseasesEye Diseases Has associated chemicals Has associated genes Has associated exposure references Eye Diseases, Hereditary Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes
4. DiseasesEye Diseases Has associated chemicals Has associated genes Has associated exposure references Optic Nerve Diseases Has associated chemicals Has associated genes Optic Atrophy Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes
5. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Eye Diseases, Hereditary Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes
6. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes
7. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Mitochondrial Diseases Has associated chemicals Has associated genes Optic Atrophy, Autosomal Dominant Has associated chemicals Has associated genes

Top ↑ Descendants

None.