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Disease Optic Atrophy, Hereditary, Leber

Name Optic Atrophy, Hereditary, Leber
Synonyms Disease, Leber's | Diseases, Leber's | Hereditary Optic Neuroretinopathies | Hereditary Optic Neuroretinopathy | Leber Disease | Leber Hereditary Optic Atrophy | Leber Hereditary Optic Neuropathy | LEBER HEREDITARY OPTIC NEUROPATHY, MODIFIER OF | Leber Optic Atrophy | Leber Optic Atrophy and Dystonia | LEBER OPTIC ATROPHY, SUSCEPTIBILITY TO | Leber Optic Neuropathy | Leber's Disease | Lebers Disease | Leber's Diseases | Leber's Hereditary Optic Atrophy | Leber's Hereditary Optic Neuropathy | Leber's Optic Atrophy | Leber's Optic Neuropathy | Lebers Optic Neuropathy | LHON | LHON, MODIFIER OF | LOAS | Neuropathy, Leber's Optic | Neuroretinopathies, Hereditary Optic | Neuroretinopathy, Hereditary Optic | Optic Atrophy, Leber | Optic Atrophy, Leber, Hereditary | Optic Atrophy, Leber Type | Optic Neuropathy, Leber's | Optic Neuroretinopathies, Hereditary | Optic Neuroretinopathy, Hereditary
Definition A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))
Categories Eye disease | Genetic disease (inborn) | Metabolic disease | Nervous system disease
MeSH® ID D029242
OMIM® IDs 308905 | 535000
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Top ↑ Ancestors

1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Cranial Nerve Diseases Has associated chemicals Has associated genes Has associated exposure references Optic Nerve Diseases Has associated chemicals Has associated genes Optic Atrophy Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Neurodegenerative Diseases Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
3. DiseasesEye Diseases Has associated chemicals Has associated genes Has associated exposure references Eye Diseases, Hereditary Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
4. DiseasesEye Diseases Has associated chemicals Has associated genes Has associated exposure references Optic Nerve Diseases Has associated chemicals Has associated genes Optic Atrophy Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
5. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Eye Diseases, Hereditary Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
6. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Heredodegenerative Disorders, Nervous System Has associated chemicals Has associated genes Optic Atrophies, Hereditary Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
7. DiseasesNutritional and Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Metabolic Diseases Has associated chemicals Has associated genes Has associated exposure references Mitochondrial Diseases Has associated chemicals Has associated genes Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes

Top ↑ Descendants

Optic Atrophy, Hereditary, Leber Has associated chemicals Has associated genes
  Marsden syndrome