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Disease CADASIL

Name CADASIL
Synonyms CADASIL | CADASIL1 | CADASILM | CASIL | CEREBRAL ARTERIOPATHY, AUTOSOMAL DOMINANT, WITH SUBCORTICAL INFARCTS AND LEUKOENCEPHALOPATHY, TYPE 1 | Cerebral Arteriopathy with Subcortical Infarcts and Leukoencephalopathy | Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy | Dementia, Hereditary Multi Infarct Type | Dementia, Hereditary Multi-Infarct Type
Definition A familial, cerebral arteriopathy mapped to chromosome 19q12, and characterized by the presence of granular deposits in small CEREBRAL ARTERIES producing ischemic STROKE; PSEUDOBULBAR PALSY; and multiple subcortical infarcts (CEREBRAL INFARCTION). CADASIL is an acronym for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy. CADASIL differs from BINSWANGER DISEASE by the presence of MIGRAINE WITH AURA and usually by the lack of history of arterial HYPERTENSION. (From Bradley et al, Neurology in Clinical Practice, 2000, p1146)
Categories Cardiovascular disease | Genetic disease (inborn) | Nervous system disease
MeSH® ID D046589
OMIM® ID 125310
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1. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Cerebral Small Vessel Diseases Has associated chemicals Has associated genes CADASIL Has associated chemicals Has associated genes
2. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Dementia, Vascular Has associated chemicals Has associated genes Has associated exposure references CADASIL Has associated chemicals Has associated genes
3. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Intracranial Arterial Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebral Arterial Diseases Has associated chemicals Has associated genes CADASIL Has associated chemicals Has associated genes
4. DiseasesNervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Central Nervous System Diseases Has associated chemicals Has associated genes Has associated exposure references Brain Diseases Has associated chemicals Has associated genes Has associated exposure references Dementia Has associated chemicals Has associated genes Has associated exposure references Dementia, Vascular Has associated chemicals Has associated genes Has associated exposure references CADASIL Has associated chemicals Has associated genes
5. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Vascular Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Cerebral Small Vessel Diseases Has associated chemicals Has associated genes CADASIL Has associated chemicals Has associated genes
6. DiseasesCardiovascular Diseases Has associated chemicals Has associated genes Has associated exposure references Vascular Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebrovascular Disorders Has associated chemicals Has associated genes Has associated exposure references Intracranial Arterial Diseases Has associated chemicals Has associated genes Has associated exposure references Cerebral Arterial Diseases Has associated chemicals Has associated genes CADASIL Has associated chemicals Has associated genes
7. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references CADASIL Has associated chemicals Has associated genes

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CADASIL Has associated chemicals Has associated genes
  Familial vascular leukoencephalopathy