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Disease Primary Myelofibrosis

Name Primary Myelofibrosis
Synonyms Agnogenic Myeloid Metaplasia | Agnogenic Myeloid Metaplasias | Bone Marrow Fibroses | Bone Marrow Fibrosis | Chronic Idiopathic Myelofibrosis | Fibroses, Bone Marrow | Fibrosis, Bone Marrow | Idiopathic Myelofibrosis | Metaplasia, Agnogenic Myeloid | Metaplasia, Myeloid | Metaplasias, Agnogenic Myeloid | Metaplasias, Myeloid | MMM, INCLUDED | Myelofibroses | Myelofibroses, Primary | Myelofibrosis | Myelofibrosis, Primary | Myelofibrosis With Myeloid Metaplasia | MYELOFIBROSIS WITH MYELOID METAPLASIA, INCLUDED | Myeloid Metaplasia | Myeloid Metaplasia, Agnogenic | Myeloid Metaplasias | Myeloid Metaplasias, Agnogenic | Myeloscleroses | Myelosclerosis | Myeloses, Nonleukemic | Myelosis, Nonleukemic | Nonleukemic Myeloses | Nonleukemic Myelosis | Primary Myelofibroses
Definition A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Categories Blood disease
MeSH® ID D055728
OMIM® ID 254450
External Links

Top ↑ Ancestors

DiseasesHemic and Lymphatic Diseases Has associated chemicals Has associated genes Has associated exposure references Hematologic Diseases Has associated chemicals Has associated genes Has associated exposure references Bone Marrow Diseases Has associated chemicals Has associated genes Myeloproliferative Disorders Has associated chemicals Has associated genes Primary Myelofibrosis Has associated chemicals Has associated genes

Top ↑ Descendants

Primary Myelofibrosis Has associated chemicals Has associated genes
  Familial myelofibrosis Has associated chemicals Has associated genes
  Panostotic fibrous dysplasia