Skip navigation

Disease Cryopyrin-Associated Periodic Syndromes

Name Cryopyrin-Associated Periodic Syndromes
Synonyms CAPS3 | Chronic Infantile Neurological, Cutaneous, and Articular Syndrome | Chronic, Infantile, Neurological, Cutaneous, Articular Syndrome | Chronic Infantile Neurologic, Cutaneous, and Articular Syndrome | Chronic Neurologic Cutaneous and Articular Syndrome | Chronic Neurologic, Cutaneous, and Articular Syndrome | CINCA | CINCA Syndrome | Cold Induced Autoinflammatory Syndrome, Familial | Cold-Induced Autoinflammatory Syndrome, Familial | Cold Urticaria, Familial | Cold Urticarias, Familial | Cryopyrin-Associated Periodic Syndrome | CRYOPYRIN-ASSOCIATED PERIODIC SYNDROME 3 | Cryopyrin Associated Periodic Syndromes | Cryopyrinopathies | Cryopyrinopathy | Familial Cold Autoinflammatory Syndrome | Familial Cold Autoinflammatory Syndrome 1 | Familial Cold Induced Autoinflammatory Syndrome | Familial Cold-Induced Autoinflammatory Syndrome | Familial Cold Urticaria | Familial Cold Urticarias | FCAS1 | Infantile Onset Multisystem Inflammatory Disease | IOMID | IOMID Syndrome | IOMID Syndromes | Muckle Wells Syndrome | Muckle-Wells Syndrome | Multisystem Inflammatory Disease, Neonatal Onset | Multisystem Inflammatory Disease, Neonatal-Onset | Neonatal Onset Multisystem Inflammatory Disease | NOMID | Periodic Syndrome, Cryopyrin-Associated | Periodic Syndromes, Cryopyrin-Associated | Prieur Griscelli Syndrome | Prieur-Griscelli Syndrome | Prieur-Griscelli Syndromes | Syndrome, Cryopyrin-Associated Periodic | Syndrome, IOMID | Syndrome, Muckle-Wells | Syndrome, Prieur-Griscelli | Syndromes, Cryopyrin-Associated Periodic | Syndromes, IOMID | Syndromes, Prieur-Griscelli | Syndromes, UDA | Syndromes, Urticaria-Deafness-Amyloidosis | Syndrome, UDA | Syndrome, Urticaria-Deafness-Amyloidosis | UDA Syndrome | UDA Syndromes | Urticaria Deafness Amyloidosis Syndrome | Urticaria-Deafness-Amyloidosis Syndrome | Urticaria-Deafness-Amyloidosis Syndromes | Urticaria, Deafness and Amyloidosis | Urticaria, Familial Cold | Urticarias, Familial Cold
Definition A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 protein mutations.
Categories Genetic disease (inborn) | Skin disease
MeSH® ID D056587
OMIM® ID 607115

Top ↑ Ancestors

1. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Hereditary Autoinflammatory Diseases Has associated chemicals Has associated genes Cryopyrin-Associated Periodic Syndromes Has associated chemicals Has associated genes
2. DiseasesSkin and Connective Tissue Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases Has associated chemicals Has associated genes Has associated exposure references Skin Diseases, Genetic Has associated chemicals Has associated genes Has associated exposure references Hereditary Autoinflammatory Diseases Has associated chemicals Has associated genes Cryopyrin-Associated Periodic Syndromes Has associated chemicals Has associated genes

Top ↑ Descendants

Cryopyrin-Associated Periodic Syndromes Has associated chemicals Has associated genes
  Cold Hypersensitivity
  FAMILIAL COLD AUTOINFLAMMATORY SYNDROME 1 Has associated chemicals Has associated genes
  Familial Cold Autoinflammatory Syndrome 2 Has associated chemicals Has associated genes
  MUCKLE-WELLS SYNDROME Has associated chemicals Has associated genes