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Disease Autoimmune Lymphoproliferative Syndrome

Name Autoimmune Lymphoproliferative Syndrome
Synonyms ALPS | ALPS1A, INCLUDED | ALPS1B, INCLUDED | ALPS2B | Autoimmune Lymphoproliferative Syndromes | Autoimmune Lymphoproliferative Syndrome Type 1, Autosomal Dominant | Autoimmune Lymphoproliferative Syndrome Type 2B | Autoimmune Lymphoproliferative Syndrome Type 2B (ALPS2B) | Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Dominant | AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE I, AUTOSOMAL DOMINANT AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IA, INCLUDED | AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE I, AUTOSOMAL RECESSIVE, INCLUDED | AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IB, INCLUDED | Autoimmune Lymphoproliferative Syndrome, Type Iib | Canale Smith Syndrome | Canale-Smith Syndrome | Canale-Smith Syndromes | Caspase 8 Deficiencies | Caspase-8 Deficiencies | Caspase 8 Deficiency | Caspase-8 Deficiency | CEDS | Deficiencies, Caspase 8 | Deficiencies, Caspase-8 | Deficiency, Caspase 8 | Deficiency, Caspase-8 | Lymphoproliferative Syndrome, Autoimmune | Lymphoproliferative Syndromes, Autoimmune | Syndrome, Autoimmune Lymphoproliferative | Syndrome, Canale Smith | Syndrome, Canale-Smith | Syndromes, Autoimmune Lymphoproliferative | Syndromes, Canale-Smith
Definition Rare congenital lymphoid disorder due to mutations in certain Fas-Fas ligand pathway genes. Known causes include mutations in FAS, TNFSF6, NRAS, CASP8, and CASP10 proteins. Clinical features include LYMPHADENOPATHY; SPLENOMEGALY; and AUTOIMMUNITY.
Categories Genetic disease (inborn) | Immune system disease | Lymphatic disease
MeSH® ID D056735
OMIM® IDs 601859 | 607271
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Top ↑ Ancestors

1. DiseasesHemic and Lymphatic Diseases Has associated chemicals Has associated genes Has associated exposure references Lymphatic Diseases Has associated chemicals Has associated genes Has associated exposure references Lymphoproliferative Disorders Has associated chemicals Has associated genes Has associated exposure references Autoimmune Lymphoproliferative Syndrome Has associated chemicals Has associated genes
2. DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities Has associated chemicals Has associated genes Has associated exposure references Genetic Diseases, Inborn Has associated chemicals Has associated genes Has associated exposure references Autoimmune Lymphoproliferative Syndrome Has associated chemicals Has associated genes
3. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Diseases Has associated chemicals Has associated genes Has associated exposure references Autoimmune Lymphoproliferative Syndrome Has associated chemicals Has associated genes
4. DiseasesImmune System Diseases Has associated chemicals Has associated genes Has associated exposure references Immunoproliferative Disorders Has associated chemicals Has associated genes Has associated exposure references Lymphoproliferative Disorders Has associated chemicals Has associated genes Has associated exposure references Autoimmune Lymphoproliferative Syndrome Has associated chemicals Has associated genes

Top ↑ Descendants

Autoimmune Lymphoproliferative Syndrome Has associated chemicals Has associated genes
  Autoimmune Lymphoproliferative Syndrome, Type IA
  Autoimmune Lymphoproliferative Syndrome, Type I, Autosomal Recessive
  Autoimmune Lymphoproliferative Syndrome, Type IB
  Autoimmune Lymphoproliferative Syndrome, Type IIA Has associated chemicals Has associated genes
  Dianzani autoimmune lymphoproliferative syndrome