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Disease Neurodevelopmental Disorders

These are exposure studies associated with the disease and all of its children.

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1–47 of 47 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Kalkbrenner AE, et al. (2018). Autism Genetic Resource Exchange (AGRE) Some air toxics were associated with autism spectrum disorder risk and severity, including some traffic-related air pollutants and newly-reported associations, but other previously reported associations with metals and volatile organic compounds were not reproducible. 1,4-dioxane | 4,4'-diphenylmethane diisocyanate | 4-dichlorobenzene | benzidine | bromoform | Carbon Disulfide | chlorobenzene | Dibenzofurans | methyl tert-butyl ether | propionaldehyde | Urethane Subjects with disease:Autism Spectrum Disorder United States Details Autism Spectrum Disorder
2. Hertz-Picciotto I, et al. (2011). Childhood Autism Risks from Genetics and the Environment (CHARGE) Children with autism/autism spectrum disorder and developmental delay were similar to typically developing controls for all polybrominated diphenyl ether congeners, but levels were high for all three groups. 2,2',3,3',4,4',5,6,6'-nonabromodiphenyl ether | 2,2',3,3',4,4',6,6'-octabromodiphenyl ether | 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | decabromobiphenyl ether | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | tribromodiphenyl ether 28 Subjects with disease:Autism Spectrum Disorder | Controls for disease:Developmental Disabilities | Subjects with disease:Developmental Disabilities United States serum 2,2',3,3',4,4',5,6,6'-nonabromodiphenyl ether | 2,2',3,3',4,4',6,6'-octabromodiphenyl ether | 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | decabromobiphenyl ether | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | tribromodiphenyl ether 28 Details
3. Forns J, et al. (2016). Norwegian Human Milk Study (HUMIS) Within a mixture of 24 toxicants measured in breast milk, p,p'-DDT was the single toxicant associated with behavioral problems at 12 months using different methods for handling numerous correlated exposures. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | oxychlordane | PCB 180 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Infants or newborns | Mothers Norway milk, human 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | oxychlordane | PCB 180 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Details Child Behavior Disorders
4. Braun JM, et al. (2014). Health Outcomes and Measures of the Environment (HOME) | National Health and Nutrition Examination Survey (NHANES) We used a semi-Bayesian hierarchical regression model to estimate associations between prenatal blood or urine concentrations of 52 suspected endocrine disrupting chemicals and autistic behaviors at 4 and 5 years of age in a prospective birth cohort of 175 mothers and their children. socioeconomic status | tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Children | Pregnant females | Study subjects United States serum | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2-ethyl-5-carboxypentyl phthalate | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Details Autism Spectrum Disorder
5. Lyall K, et al. (2017). Early Markers for Autism (EMA) | Project Baby's Breath (PBB) The overall pattern of our results suggests increases in risk of autism spectrum disorder and intellectual disability without autism with prenatal exposure to higher levels of a number of organochlorine compounds, particularly polychlorinated biphenyl ethers. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | nonachlor | PCB 180 | Polychlorinated Biphenyls Children | Pregnant females United States serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | nonachlor | PCB 180 | Polychlorinated Biphenyls Details Autism Spectrum Disorder | Intellectual Disability | Prenatal Exposure Delayed Effects
6. Lyall K, et al. (2018). Early Markers for Autism (EMA) Results from this large case-control study with prospectively collected prenatal measurements do not support the hypothesis that prenatal exposure to per- and polyfluoroalkyl substances is positively associated with autism spectrum disorder or intellectual disability. 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | N-ethyl perfluorooctane sulfonamido acetate | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Subjects with disease:Autism Spectrum Disorder | Children | Subjects with disease:Intellectual Disability | Pregnant females United States serum 2-(N-methylperfluorooctanesulfonamido)acetic acid | hexadecafluoro-nonanoic acid | N-ethyl perfluorooctane sulfonamido acetate | perfluorodecanoic acid | perfluorohexanesulfonic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid Details Autism Spectrum Disorder | Intellectual Disability
7. Fortenberry GZ, et al. (2014). Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) | National Health and Nutrition Examination Survey (NHANES) The objective of this study was to investigate the relationship between in utero exposure to chlorpyrifos, chlorpyrifos-methyl, and/or 3,5,6-trichloro-2-pyridinol (TCPY) and ADHD in school-age Mexican children using TCPY as a biomarker of exposure. sex 3,5,6-trichloro-2-pyridinol | Chlorpyrifos | chlorpyrifos-methyl | Lead Children | Pregnant females Mexico blood | urine 3,5,6-trichloro-2-pyridinol | Lead Details Attention Deficit Disorder with Hyperactivity | behavior | cognition
8. Yu CJ, et al. (2016). This case-control study found that 4-nonylphenol exposure was not a risk factor for Attention Deficit Disorder with Hyperactivity in school-age children in Taiwan after adjusting for confounding factors. 4-nonylphenol | Lead Controls for disease:Attention Deficit Disorder with Hyperactivity | Subjects with disease:Attention Deficit Disorder with Hyperactivity | Children Taiwan, Province of China blood | urine 4-nonylphenol | Lead Details Attention Deficit Disorder with Hyperactivity
9. Kalkbrenner AE, et al. (2010). Autism and Developmental Disabilities Monitoring Network (ADDM) Our screening design was limited by exposure misclassification of air pollutants and the use of an alternate developmental disorder as the control group, both of which may have biased results toward the null. Despite these limitations, methylene chloride, quinoline, and styrene emerged (based on this analysis and prior epidemiologic evidence) as candidates that warrant further investigation for a possible role in autism etiology. Air Pollutants United States air 1,1,2,2-tetrachloroethane | 1,3-butadiene | 1,3-dichloro-1-propene | Acetaldehyde | Acrolein | Acrylonitrile | Arsenicals | Benzene | Beryllium | Cadmium Compounds | Carbon Tetrachloride | Chloroform | Chromium Compounds | Coke | ethylbenzene | Ethylene Dibromide | ethylene dichloride | Ethylene Oxide | Formaldehyde | Hexachlorobenzene | Hexanes | hydrazine | Lead | Manganese Compounds | Mercury Compounds | Methylene Chloride | methyl tert-butyl ether | Nickel | Polychlorinated Biphenyls | Polycyclic Aromatic Hydrocarbons | propionaldehyde | propylene dichloride | quinoline | Styrene | Tetrachloroethylene | Toluene | Trichloroethylene | Vehicle Emissions | Vinyl Chloride | Xylenes Details Autism Spectrum Disorder
10. Windham GC, et al. (2006). Our results suggest a potential association between autism and estimated metal concentrations, and possibly chlorinated solvents, in ambient air around the birth residence, requiring confirmation and more refined exposure assessment in future studies. Air Pollutants Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children United States air, ambient Arsenic | Benzene | Cadmium | Chromium | ethylbenzene | hydrazine | Hydrocarbons, Chlorinated | Lead | Manganese | Mercury | Metals, Heavy | Methylene Chloride | Nickel | Particulate Matter | Polycyclic Aromatic Hydrocarbons | Solvents | Styrene | Tetrachloroethylene | Toluene | Trichloroethylene | Vinyl Chloride | Xylenes Details Autism Spectrum Disorder
11. Chen G, et al. (2018). Exposures to air pollutant particulate matter (PM1, PM2.5 and PM10) during the first three years of life were associated with the increased risk of autism spectrum disorder and there appeared to be stronger effects of ambient pollution in the second and the third years after birth. age Air Pollutants Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children China air, ambient Particulate Matter Details Autism Spectrum Disorder
12. Volk HE, et al. (2011). Childhood Autism Risks from Genetics and the Environment (CHARGE) Autism was also associated with residential proximity to a freeway during the third trimester. Air Pollutants Study subjects United States Details Autistic Disorder
13. Newman NC, et al. (2013). Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS) Elemental carbon attributed to traffic exposure during infancy was associated with higher Hyperactivity scores in children; this association was limited to children whose mothers had more than a high school education. Air Pollutants | Carbon | Particulate Matter Children United States Particulate Matter Details Attention Deficit Disorder with Hyperactivity | Conduct Disorder
14. Chiu YH, et al. (2016). Asthma Coalition on Community, Environment, and Social Stress (ACCESS) Increased particulate matter PM2.5 exposure in specific prenatal windows may be associated with poorer function across memory and attention domains with variable associations based on sex. sex Air Pollutants | Vehicle Emissions Children | Fetuses | Pregnant females United States air, ambient Particulate Matter Details Neurodevelopmental Disorders | Prenatal Exposure Delayed Effects | learning or memory | memory
15. Nevison CD. (2014). Temporal trends in autism were constructed both by tracking prevalence at a constant age in a series of historical IDEA reports and by computing prevalence from age-resolved snapshots in individual, recent IDEA reports. Aluminum | glyphosate | Halogenated Diphenyl Ethers | Hydrocarbons, Chlorinated | Lead | Vehicle Emissions Children United States Details Autism Spectrum Disorder
16. Rodrigues EG, et al. (2016). Where blood lead levels are high, lead is associated with decreased cognitive scores (and effects of other metals are not detected); however, in the setting of lower lead levels, the adverse effects of arsenic and manganese on neurodevelopment are observed. age | diet Arsenic | Lead | Manganese Children | Infants or newborns | Pregnant females Bangladesh blood | water, well Arsenic | Lead | Manganese Details Motor Skills Disorders | Neurodevelopmental Disorders | cognition | motor behavior
17. Wasserman GA, et al. (2007). Exposure to arsenic from drinking water was associated with reduced intellectual function before and after adjusting for water manganese for blood lead levels, and for sociodemographic features. diet Arsenic | Lead | Manganese Children Bangladesh blood | urine | water, drinking Arsenic | Lead | Manganese Details Arsenic Poisoning | Learning Disorders
18. Rahman SM, et al. (2016). Maternal and Infant Nutrition Interventions in Matlab (MINIMat) Elevated prenatal water manganese exposure was positively associated with cognitive function in girls, while boys appeared unaffected; however, early-life exposure appeared to adversely affect children's behavior. age | diet | sex Arsenic | Manganese Children | Pregnant females Bangladesh water, drinking Arsenic | Manganese Details Child Behavior Disorders | cognition
19. Evans SF, et al. (2014). Study for Future Families (SFF) We report an association between maternal urinary bisphenol A concentrations during pregnancy and sexually dimorphic behaviors in school age children. sex bisphenol A Children | Fetuses | Pregnant females United States urine bisphenol A Details Anxiety Disorders | Attention Deficit and Disruptive Behavior Disorders | Conduct Disorder | aggressive behavior | behavior
20. Ciesielski T, et al. (2012). National Health and Nutrition Examination Survey (NHANES) These findings suggest that children who have higher urinary cadmium concentrations may have increased risk of both learning disability and special education. Importantly, we observed these associations at exposure levels that were previously considered to be without adverse effects, and these levels are common among U.S. children. race | socioeconomic status Cadmium Children United States urine Cadmium Details Attention Deficit Disorder with Hyperactivity | Learning Disorders
21. Szkup-Jabłońska M, et al. (2012). The effect of lead on the developing child has behavioral consequences including attention disorders, hyperactivity, and impulsive behavior; no effect of cadmium was shown. age Cadmium | Lead Subjects with disease:Attention Deficit Disorder with Hyperactivity | Subjects with disease:Child Behavior Disorders | Children Poland blood Cadmium | Lead Details Attention Deficit Disorder with Hyperactivity
22. Forns J, et al. (2016). BRain dEvelopment and Air polluTion ultrafine particles in scHool childrEn (BREATHE) Project In our study population of 7- to 11-year-old children residing in Barcelona, exposure to TRAPs at school was associated with increased behavioral problems in schoolchildren. Carbon | Nitrogen Dioxide | Soot Children Spain air Carbon | Nitrogen Dioxide | Soot Details Child Behavior Disorders
23. Sagiv SK, et al. (2018). Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) These findings contribute mixed evidence linking organophosphate pesticide exposures with traits related to developmental disorders like autism spectrum disorders. Chlorpyrifos | Diazinon | diethyl phosphate | dimethyl phosphate | Malathion | methyl demeton | Organophosphates | Pesticides Children | Pregnant females United States urine Chlorpyrifos | Diazinon | diethyl phosphate | dimethyl phosphate | Malathion | methyl demeton | Organophosphates | Pesticides Details Autism Spectrum Disorder
24. van Wendel de Joode B, et al. (2016). Our findings indicate that children living near banana and plantain plantations are exposed to pesticides that may affect their neurodevelopment, which for certain domains may differ between boys and girls. sex Chlorpyrifos | mancozeb | Pyrethrins Children Costa Rica urine 3,5,6-trichloro-2-pyridinol | 3-phenoxybenzoic acid | Ethylenethiourea Details Attention Deficit Disorder with Hyperactivity | behavior | cognition | learned vocalization behavior or vocal learning | memory | visual perception
25. Marks AR, et al. (2010). Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) In utero dialkyl phosphates (DAPs) and, to a lesser extent, postnatal DAPs were associated adversely with attention as assessed by maternal report, psychometrician observation, and direct assessment. These associations were somewhat stronger at 5 years than at 3.5 years and were stronger in boys. age | sex diethyl phosphate | dimethyl phosphate | Organophosphates Children | Mothers United States urine diethyl phosphate | dimethyl phosphate | Organophosphates Details Attention Deficit Disorder with Hyperactivity
26. Blaurock-Busch E, et al. (2011). We assessed a spectrum of trace elements and heavy metals in hair and urine of both autistic and control groups to focus on the participants' past and present exposure. Elements | Metals Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children Saudi Arabia hair | urine Aluminum | Antimony | Arsenic | Barium | Beryllium | Bismuth | Boron | Cadmium | Calcium | Cerium | Cesium | Chromium | Cobalt | Copper | Gallium | Germanium | Iodine | Iron | Lead | Lithium | Magnesium | Manganese | Mercury | Molybdenum | Nickel | Palladium | Platinum | Selenium | Silver | Strontium | Thallium | Tin | Titanium | Tungsten | Uranium | Vanadium | Zinc | Zirconium Details
27. Sayal K, et al. (2014). Avon Longitudinal Study of Parents and Children (ALSPAC) The objective of the study is to investigate whether episodic binge pattern of alcohol consumption during pregnancy is independently associated with child mental health and academic outcomes. Ethanol Children United Kingdom Details Attention Deficit Disorder with Hyperactivity | Prenatal Exposure Delayed Effects | cognition
28. Herbstman JB, et al. (2010). This epidemiologic study demonstrates neurodevelopmental effects in relation to cord blood polybrominated diphenyl ether concentrations. Halogenated Diphenyl Ethers Infants or newborns United States blood, cord 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | PBB 153 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether Details Intellectual Disability | Psychomotor Disorders | cognition
29. Roy A, et al. (2009). Overall, this study suggests that lead exposure affects behavior across multiple domains, including anxiety and social behavior. The results also suggest that executive functions and attention are especially vulnerable to insult by lead among young children. Lead Children India blood Lead Details Anxiety Disorders | Attention Deficit Disorder with Hyperactivity | behavior | cognition
30. Huang S, et al. (2016). Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) In this population of Mexican children, current blood lead level among children with low exposure (<=5 micrograms per deciliter) was positively associated with hyperactive/impulsive behaviors, but not with inattentiveness. Lead Children Mexico blood Lead Details Attention Deficit Disorder with Hyperactivity
31. Rahbar MH, et al. (2015). Jamaican Autism Study In univariable general linear models, we found a significant difference between geometric mean blood lead concentrations of autism spectrum disorder cases and controls; however, after controlling for potential confounders, there were no significant differences, and our results do not support an association between blood lead and autism spectrum disorder in Jamaican children. Lead Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children Jamaica blood Lead Details Autism Spectrum Disorder
32. Jedrychowski W, et al. (2008). The data obtained from our study may suggest that a subtle neurotoxic impact of low-level prenatal lead exposure occurs in infants from the Krakow inner city area. Lead Infants or newborns Poland blood, cord Lead Details Developmental Disabilities | cognition
33. Braun JM, et al. (2008). National Health and Nutrition Examination Survey (NHANES) These results suggest that prenatal tobacco exposure and environmental lead exposure contribute substantially to conduct disorder in U.S. children. Lead | Tobacco Smoke Pollution Children United States blood | serum Cotinine | Lead Details Conduct Disorder
34. Savabieasfahani M, et al. (2015). Exposure to mixtures of metals that can result from high-temperature explosions of war may have additive or synergistic effects that can alter toxicity, especially in developing children; a spectrum of neurodevelopmental disorders are appearing in Iraqi cities where bombing and military events have led to increased public exposures to toxic metals. Magnesium | Metals | Titanium Children | Controls for disease:Congenital Abnormalities | Subjects with disease:Congenital Abnormalities | Controls for disease:Neurodevelopmental Disorders | Subjects with disease:Neurodevelopmental Disorders Iran, Islamic Republic of|Iraq hair Aluminum | Arsenic | Cadmium | Chromium | Cobalt | Copper | Iron | Lead | Magnesium | Manganese | Mercury | Molybdenum | Nickel | Selenium | Titanium | Uranium | Vanadium | Zinc Details
35. Rahbar MH, et al. (2014). Jamaican Autism Study Our study results found no statistically significant association between blood manganese concentrations and Autism Spectrum Disorder status. Manganese Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children Jamaica blood Manganese Details Autism Spectrum Disorder
36. Hertz-Picciotto I, et al. (2010). After accounting for dietary and other differences in mercury exposures, total mercury in blood was neither elevated nor reduced in CHARGE study preschoolers with autism or autism spectrum disorder compared with unaffected controls, and resembled those of nationally representative samples. Mercury Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children | Controls for disease:Developmental Disabilities | Subjects with disease:Developmental Disabilities United States blood Mercury Details Autism Spectrum Disorder
37. Engström K, et al. (2016). Seychelles Child Development Study (SCDS) Genetic variation in ABC transporter genes was associated with maternal hair mercury concentrations, and with neurodevelopment in infants. genetics Mercury | Methylmercury Compounds Subjects with gene influence:ABCB1 | Subjects with gene influence:ABCC1 | Subjects with gene influence:ABCC2 | Infants or newborns | Pregnant females Seychelles hair Mercury Details Neurodevelopmental Disorders | Prenatal Exposure Delayed Effects
38. Al-Farsi YM, et al. (2013). This study documents the levels of heavy metals and essential minerals in hair samples of children with autism spectrum disorders in Muscat (Oman), and corroborates previous studies in different parts of the world indicating the presence of elevated levels of heavy metals and selective depletion of essential minerals in the hair of children with autism spectrum disorders. disease Metals, Heavy | Minerals Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Children Oman hair Aluminum | Barium | Boron | Cadmium | Calcium | Chromium | Cobalt | Copper | Iron | Lead | Magnesium | Manganese | Molybdenum | Nickel | Phosphorus | Potassium | Silicon | Sodium | Sulfur | Vanadium | Zinc Details
39. Ruckart PZ, et al. (2004). Our findings suggest that methyl parathion might be associated with subtle changes to short-term memory and attention and contribute to problems with motor skills and some behaviors, but the results of the study are not conclusive. Methyl Parathion Children United States Details Cognition Disorders | Motor Skills Disorders | behavior | memory
40. Gong T, et al. (2017). Among children born between 1993 and 2007 in Stockholm County, we found that pre- and postnatal exposure to either nitrogen oxides or particulate matter with diameter <=10 microns was not associated with autism spectrum disorders overall, with or without intellectual disability. Nitrogen Oxides | Particulate Matter Controls for disease:Autism Spectrum Disorder | Subjects with disease:Autism Spectrum Disorder | Fetuses | Infants or newborns Sweden air Nitrogen Oxides | Particulate Matter Details Autism Spectrum Disorder
41. Eskenazi B, et al. (2010). Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) PON1 was associated with child neurobehavioral development, but additional research is needed to confirm whether it modifies the relation with in utero organophosphate exposure. genetics Organophosphates Children | Mothers United States urine diethyl phosphate | dimethyl phosphate | Organophosphates | PON1 Details Developmental Disabilities | brain development
42. Hoffman K, et al. (2010). National Health and Nutrition Examination Survey (NHANES) Our results, using cross-sectional data, are consistent with increased odds of attention deficit/hyperactivity disorder in children with higher serum polyfluoroalkyl chemicals levels. sex | tobacco perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Children United States serum perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid Details Attention Deficit Disorder with Hyperactivity
43. Handal AJ, et al. (2007). Residence in communities with high potential for exposure to organophosphate and carbamate pesticides was associated with poorer neurobehavioral development of the child, even after controlling for major determinants of delayed development. Malnourished populations may be particularly vulnerable to neurobehavioral effects of pesticide exposure. diet | socioeconomic status Pesticides Children | Infants or newborns Ecuador Details Developmental Disabilities
44. Park S, et al. (2014). The results of this study suggest a possible association between urinary phthalate metabolite concentrations and poor attentional performances in attention-deficit hyperactivity disorder patients, as well as a genetic influence on this association, especially for dopamine receptor D4 genotype. disease | genetics Phthalic Acids Subjects with disease:Attention Deficit Disorder with Hyperactivity | Children | Subjects with gene influence:DRD4 Korea, Republic of urine mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monobutyl phthalate Details learning
45. Jedrychowski WA, et al. (2015). To our knowledge, this is the first epidemiologic study showing that prenatal polycyclic aromatic hydrocarbon (PAH) exposure measured by cord blood PAH-DNA adducts is associated with cognitive dysfunction (depressed verbal IQ index) assessed by the WISC-R test, which is the commonly used instrument for measuring intelligence of children. Polycyclic Aromatic Hydrocarbons Children Poland blood, cord polycyclic aromatic hydrocarbons-DNA adduct Details Cognition Disorders | Learning Disorders | cognition
46. Richardson JR, et al. (2015). National Health and Nutrition Examination Survey (NHANES) Epidemiologic data reveal that children aged 6-15 with detectable levels of pyrethroid metabolites in their urine were more than twice as likely to be diagnosed with attention-deficit hyperactivity disorder. Pyrethrins Children United States urine 3-phenoxybenzoic acid Details Attention Deficit Disorder with Hyperactivity
47. Cieslak K, et al. (2014). This study demonstrates a relationship of low vitamin D levels with increased cellular aging in females, and also demonstrates potential sex-specific profiles among schizophrenia cases with hypovitaminosis. sex Vitamin D Subjects with disease:Schizophrenia | Subjects with disease:Vitamin D Deficiency United States serum Vitamin D Details Anhedonia | Developmental Disabilities | Psychotic Disorders | Schizophrenia | Social Communication Disorder | aggressive behavior | cell aging | regulation of telomere maintenance via telomere lengthening | social behavior
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