Alzheimer Disease

Name	Alzheimer Disease
Synonyms	Acute Confusional Senile Dementia \| AD \| AD1, INCLUDED \| Alzheimer Dementia, Presenile \| Alzheimer Disease, Early Onset \| ALZHEIMER DISEASE, EARLY-ONSET, WITH CEREBRAL AMYLOID ANGIOPATHY, INCLUDED \| Alzheimer Disease, Late Onset \| ALZHEIMER DISEASE, PROTECTION AGAINST, INCLUDED \| Alzheimer's Disease \| Alzheimer's Disease, Focal Onset \| Alzheimer Type Dementia \| Alzheimer Type Senile Dementia \| Dementia, Alzheimer Type \| Dementia, Presenile \| Dementia, Presenile Alzheimer \| Dementia, Primary Senile Degenerative \| Dementia, Senile \| Dementias, Presenile \| Dementias, Senile \| Disease, Alzheimer \| Disease, Alzheimer's \| Early Onset Alzheimer Disease \| Focal Onset Alzheimer's Disease \| Late Onset Alzheimer Disease \| Presenile Alzheimer Dementia \| PRESENILE AND SENILE DEMENTIA ALZHEIMER DISEASE, FAMILIAL, 1, INCLUDED \| Presenile Dementia \| Presenile Dementias \| Primary Senile Degenerative Dementia \| Senile Dementia \| Senile Dementia, Acute Confusional \| Senile Dementia, Alzheimer Type \| Senile Dementias
Definition	A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Categories	Mental disorder \| Nervous system disease
MeSH^® ID	D000544
OMIM^® ID	104300

Top ↑ Ancestors

1.	Diseases ← Nervous System Diseases ← Central Nervous System Diseases ← Brain Diseases ← Dementia ← Alzheimer Disease
2.	Diseases ← Nervous System Diseases ← Neurodegenerative Diseases ← Tauopathies ← Alzheimer Disease
3.	Diseases ← Mental Disorders ← Delirium, Dementia, Amnestic, Cognitive Disorders ← Dementia ← Alzheimer Disease

Top ↑ Descendants

Alzheimer Disease
	Alzheimer Disease 10
	Alzheimer Disease 11
	Alzheimer Disease 12
	Alzheimer Disease 13
	Alzheimer Disease 14
	Alzheimer Disease 15
	Alzheimer Disease 16
	Alzheimer Disease 2
	Alzheimer Disease 5
	Alzheimer Disease 6
	Alzheimer Disease 7
	Alzheimer Disease 8
	Alzheimer Disease 9
	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
	Alzheimer disease, familial
	Alzheimer Disease, Familial, 1
	Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Apraxia
	Alzheimer Disease, Familial, 3, with Spastic Paraparesis and Unusual Plaques
	Alzheimer Disease, Familial Early-Onset, With Coexisting Amyloid And Prion Pathology
	Alzheimer disease, familial, type 3
	Alzheimer disease type 1
	Alzheimer disease type 2
	Alzheimer disease type 4
	Alzheimer's disease without Neurofibrillary tangles
	Lewy Body Variant of Alzheimer Disease
	Presenile And Senile Dementia