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Gene PHF20

These diseases are associated with the PHF20 gene. This gene has either a curated association to a disease (M marker/mechanism and/or T therapeutic) or an inferred association via a curated chemical interaction.

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1–50 of 816 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Drug-Induced Liver Injury  
19 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Arsenic | Benzo(a)pyrene | tert-Butylhydroperoxide | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | cobaltous chloride | Copper Sulfate | 9,10-Dimethyl-1,2-benzanthracene | Lead | Phenobarbital | pirinixic acid | Plant Extracts | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 67.38 395
2. Prenatal Exposure Delayed Effects  
13 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Arsenic | Atrazine | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Lead | Methylcholanthrene | Phenobarbital | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 56.72 95
3. Fetal Growth Retardation  
10 chemicals: Arsenic | Atrazine | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Lead | Phenobarbital | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 51.41 22
4. Neoplasms  
13 chemicals: Arsenic | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Lead | Methylcholanthrene | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 50.78 24
5. Necrosis  
14 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | tert-Butylhydroperoxide | Cadmium Chloride | cobaltous chloride | Methylcholanthrene | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 47.94 119
6. Hyperplasia  
11 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | tert-Butylhydroperoxide | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin 46.95 23
7. Precancerous Conditions  
11 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 46.85 48
8. Fatty Liver  
11 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 45.85 35
9. Hypertrophy  
9 chemicals: Acetaminophen | Benzo(a)pyrene | Cadmium Chloride | Copper Sulfate | Phenobarbital | pirinixic acid | Plant Extracts | Progesterone | Tetrachlorodibenzodioxin 43.00 17
10. Neural Tube Defects  
9 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | sodium arsenite | Valproic Acid | Vitamin E 42.69 60
11. Cell Transformation, Neoplastic  
10 chemicals: Arsenic | Benzo(a)pyrene | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | Plant Extracts | sodium arsenite | Vitamin E 42.09 45
12. Learning Disorders  
10 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Arsenic | Atrazine | Benzo(a)pyrene | Copper Sulfate | Lead | Phenobarbital | sodium arsenite | Valproic Acid 41.49 29
13. Inflammation  
12 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | cobaltous chloride | Copper Sulfate | 9,10-Dimethyl-1,2-benzanthracene | Plant Extracts | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 41.18 36
14. Cognition Disorders  
10 chemicals: Arsenic | Atrazine | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | Lead | Phenobarbital | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 39.43 51
15. Kidney Diseases  
12 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | cobaltous chloride | Lead | Phenobarbital | Plant Extracts | Progesterone | sodium arsenite | Valproic Acid | Vitamin E 39.42 65
16. Liver Neoplasms, Experimental  
10 chemicals: Acetaminophen | Benzo(a)pyrene | Chlorodiphenyl (54% Chlorine) | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin 37.50 116
17. Neurotoxicity Syndromes  
9 chemicals: Arsenic | Benzo(a)pyrene | Cadmium Chloride | Copper Sulfate | Phenobarbital | Plant Extracts | Progesterone | sodium arsenite | Vitamin E 36.87 13
18. Fetal Death  
7 chemicals: Acetaminophen | Arsenic | Phenobarbital | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 35.78 16
19. Carcinoma, Hepatocellular  
10 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Chlorodiphenyl (54% Chlorine) | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 35.10 57
20. Lung Neoplasms  
10 chemicals: Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Lead | Methylcholanthrene | Phenobarbital | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 34.93 67
21. Edema  
10 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | Plant Extracts | Tetrachlorodibenzodioxin | Valproic Acid 34.11 27
22. Proteinuria  
9 chemicals: Acetaminophen | Arsenic | Cadmium Chloride | cobaltous chloride | Lead | Phenobarbital | sodium arsenite | Valproic Acid | Vitamin E 33.76 15
23. Skin Neoplasms  
8 chemicals: Arsenic | Benzo(a)pyrene | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | tert-Butylhydroperoxide | 9,10-Dimethyl-1,2-benzanthracene | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin 32.72 66
24. Micronuclei, Chromosome-Defective  
7 chemicals: Atrazine | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | Tetrachlorodibenzodioxin 32.66 10
25. Neurobehavioral Manifestations  
7 chemicals: Acetaminophen | Benzo(a)pyrene | Lead | Methylcholanthrene | Phenobarbital | Plant Extracts | Valproic Acid 32.17 10
26. Hepatomegaly  
8 chemicals: Acetaminophen | Arsenic | Cadmium Chloride | Phenobarbital | pirinixic acid | Plant Extracts | Tetrachlorodibenzodioxin | Valproic Acid 31.46 55
27. Liver Neoplasms  
9 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin 31.36 55
28. Infertility, Male  
7 chemicals: Atrazine | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | Lead | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 30.62 9
29. Neoplasms, Experimental  
8 chemicals: Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin 30.47 24
30. Adenocarcinoma  
8 chemicals: Atrazine | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | Progesterone | sodium arsenite | Valproic Acid | Vitamin E 29.67 19
31. Carcinoma  
8 chemicals: Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin 29.48 14
32. Anemia  
8 chemicals: Acetaminophen | Arsenic | Lead | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 29.22 10
33. Memory Disorders  
8 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Arsenic | Benzo(a)pyrene | Lead | Phenobarbital | Plant Extracts | sodium arsenite | Valproic Acid 28.90 27
34. Liver Diseases  
8 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Phenobarbital | Plant Extracts | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 28.80 34
35. Poisoning  
8 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Atrazine | Cadmium Chloride | Methylcholanthrene | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 28.01 10
36. Hypertension  
10 chemicals: Acetaminophen | Arsenic | cobaltous chloride | Lead | Plant Extracts | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 27.84 41
37. Nerve Degeneration  
8 chemicals: Chlorodiphenyl (54% Chlorine) | Lead | Phenobarbital | Plant Extracts | Progesterone | sodium arsenite | Valproic Acid | Vitamin E 27.36 11
38. Atherosclerosis  
7 chemicals: Arsenic | Benzo(a)pyrene | Chlorodiphenyl (54% Chlorine) | Methylcholanthrene | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 27.16 18
39. Hyperkinesis  
8 chemicals: Atrazine | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | Lead | Phenobarbital | Plant Extracts | sodium arsenite | Valproic Acid 26.66 24
40. Heart Defects, Congenital  
6 chemicals: Benzo(a)pyrene | Phenobarbital | Progesterone | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 26.57 18
41. Weight Loss  
7 chemicals: Atrazine | Cadmium Chloride | pirinixic acid | Plant Extracts | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 26.07 16
42. Cardiovascular Abnormalities  
5 chemicals: Arsenic | Plant Extracts | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 25.81 7
43. Urinary Bladder Neoplasms  
7 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | Methylcholanthrene | Phenobarbital | sodium arsenite 25.62 27
44. Arteriosclerosis  
5 chemicals: Acetaminophen | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Vitamin E 25.27 3
45. Drug-Related Side Effects and Adverse Reactions  
8 chemicals: Acetaminophen | Cadmium Chloride | Methylcholanthrene | Phenobarbital | Plant Extracts | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 24.44 36
46. Disease Models, Animal  
6 chemicals: Acetaminophen | Copper Sulfate | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Progesterone | Valproic Acid 24.42 23
47. Adenoma  
6 chemicals: Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | Plant Extracts | sodium arsenite 24.39 19
48. Acute Kidney Injury  
8 chemicals: Acetaminophen | Cadmium Chloride | Copper Sulfate | Phenobarbital | pirinixic acid | Plant Extracts | sodium arsenite | Vitamin E 24.30 54
49. Cholestasis  
7 chemicals: Acetaminophen | Methylcholanthrene | Phenobarbital | pirinixic acid | Progesterone | Valproic Acid | Vitamin E 24.16 12
50. Nervous System Diseases  
7 chemicals: Arsenic | Lead | Phenobarbital | Progesterone | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 23.67 19
1–50 of 816 results.