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Gene PHF20

These diseases are associated with the PHF20 gene. This gene has either a curated association to a disease (M marker/mechanism and/or T therapeutic) or an inferred association via a curated chemical interaction.

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1–50 of 749 results.
  Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Drug-Induced Liver Injury  
18 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Arsenic | Benzo(a)pyrene | tert-Butylhydroperoxide | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | cobaltous chloride | Copper Sulfate | 9,10-Dimethyl-1,2-benzanthracene | Lead | Phenobarbital | pirinixic acid | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 65.58 366
2. Neoplasms  
12 chemicals: Arsenic | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Lead | Methylcholanthrene | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 47.23 23
3. Prenatal Exposure Delayed Effects  
11 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Arsenic | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Lead | Methylcholanthrene | Phenobarbital | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 47.02 91
4. Fetal Growth Retardation  
9 chemicals: Arsenic | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Lead | Phenobarbital | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 46.86 20
5. Necrosis  
13 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | tert-Butylhydroperoxide | Cadmium Chloride | cobaltous chloride | Methylcholanthrene | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 45.28 111
6. Neural Tube Defects  
9 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | sodium arsenite | Valproic Acid | Vitamin E 44.03 59
7. Precancerous Conditions  
10 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 42.49 46
8. Fatty Liver  
10 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 42.21 30
9. Hypertrophy  
8 chemicals: Acetaminophen | Benzo(a)pyrene | Cadmium Chloride | Copper Sulfate | Phenobarbital | pirinixic acid | Progesterone | Tetrachlorodibenzodioxin 38.12 15
10. Inflammation  
11 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | cobaltous chloride | Copper Sulfate | 9,10-Dimethyl-1,2-benzanthracene | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 38.03 21
11. Cell Transformation, Neoplastic  
9 chemicals: Arsenic | Benzo(a)pyrene | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | sodium arsenite | Vitamin E 37.89 42
12. Hyperplasia  
9 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | tert-Butylhydroperoxide | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin 37.42 22
13. Learning Disorders  
9 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetaminophen | Arsenic | Benzo(a)pyrene | Copper Sulfate | Lead | Phenobarbital | sodium arsenite | Valproic Acid 37.34 27
14. Fetal Death  
7 chemicals: Acetaminophen | Arsenic | Phenobarbital | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 36.63 16
15. Kidney Diseases  
11 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | cobaltous chloride | Lead | Phenobarbital | Progesterone | sodium arsenite | Valproic Acid | Vitamin E 36.23 57
16. Proteinuria  
9 chemicals: Acetaminophen | Arsenic | Cadmium Chloride | cobaltous chloride | Lead | Phenobarbital | sodium arsenite | Valproic Acid | Vitamin E 34.77 15
17. Liver Neoplasms, Experimental  
9 chemicals: Acetaminophen | Benzo(a)pyrene | Chlorodiphenyl (54% Chlorine) | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin 33.74 111
18. Neurotoxicity Syndromes  
8 chemicals: Arsenic | Benzo(a)pyrene | Cadmium Chloride | Copper Sulfate | Phenobarbital | Progesterone | sodium arsenite | Vitamin E 32.48 10
19. Carcinoma, Hepatocellular  
9 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Chlorodiphenyl (54% Chlorine) | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 31.50 53
20. Edema  
9 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | pirinixic acid | Tetrachlorodibenzodioxin | Valproic Acid 30.76 18
21. Cognition Disorders  
8 chemicals: Arsenic | Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | Lead | Phenobarbital | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 30.54 48
22. Skin Neoplasms  
7 chemicals: Arsenic | Benzo(a)pyrene | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | tert-Butylhydroperoxide | 9,10-Dimethyl-1,2-benzanthracene | sodium arsenite | Tetrachlorodibenzodioxin 28.49 64
23. Liver Neoplasms  
8 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | pirinixic acid | sodium arsenite | Tetrachlorodibenzodioxin 28.35 51
24. Micronuclei, Chromosome-Defective  
6 chemicals: Benzo(a)pyrene | Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | Tetrachlorodibenzodioxin 28.00 8
25. Neurobehavioral Manifestations  
6 chemicals: Acetaminophen | Benzo(a)pyrene | Lead | Methylcholanthrene | Phenobarbital | Valproic Acid 27.80 9
26. Hepatomegaly  
7 chemicals: Acetaminophen | Arsenic | Cadmium Chloride | Phenobarbital | pirinixic acid | Tetrachlorodibenzodioxin | Valproic Acid 27.48 49
27. Heart Defects, Congenital  
6 chemicals: Benzo(a)pyrene | Phenobarbital | Progesterone | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 27.07 18
28. Lung Neoplasms  
8 chemicals: Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 26.94 64
29. Neoplasms, Experimental  
7 chemicals: Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | sodium arsenite | Tetrachlorodibenzodioxin 26.45 16
30. Urinary Bladder Neoplasms  
7 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Cadmium Chloride | Methylcholanthrene | Phenobarbital | sodium arsenite 26.42 26
31. Infertility, Male  
6 chemicals: Cadmium Chloride | Chlorodiphenyl (54% Chlorine) | Lead | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 26.01 7
32. Arteriosclerosis  
5 chemicals: Acetaminophen | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Vitamin E 25.68 3
33. Adenocarcinoma  
7 chemicals: Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Phenobarbital | Progesterone | sodium arsenite | Valproic Acid | Vitamin E 25.64 18
34. Carcinoma  
7 chemicals: Arsenic | Benzo(a)pyrene | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Phenobarbital | sodium arsenite | Tetrachlorodibenzodioxin 25.64 11
35. Disease Models, Animal  
6 chemicals: Acetaminophen | Copper Sulfate | 9,10-Dimethyl-1,2-benzanthracene | Methylcholanthrene | Progesterone | Valproic Acid 25.55 22
36. Memory Disorders  
7 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Arsenic | Benzo(a)pyrene | Lead | Phenobarbital | sodium arsenite | Valproic Acid 25.00 22
37. Hypertension  
9 chemicals: Acetaminophen | Arsenic | cobaltous chloride | Lead | Progesterone | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 24.91 34
38. Liver Diseases  
7 chemicals: Acetaminophen | Arsenic | Benzo(a)pyrene | Phenobarbital | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 24.87 31
39. Cholestasis  
7 chemicals: Acetaminophen | Methylcholanthrene | Phenobarbital | pirinixic acid | Progesterone | Valproic Acid | Vitamin E 24.77 12
40. Nervous System Diseases  
7 chemicals: Arsenic | Lead | Phenobarbital | Progesterone | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 24.36 19
41. Nerve Degeneration  
7 chemicals: Chlorodiphenyl (54% Chlorine) | Lead | Phenobarbital | Progesterone | sodium arsenite | Valproic Acid | Vitamin E 23.83 9
42. Atherosclerosis  
6 chemicals: Arsenic | Benzo(a)pyrene | Methylcholanthrene | sodium arsenite | Tetrachlorodibenzodioxin | Vitamin E 23.21 16
43. Brain Diseases  
6 chemicals: Acetaminophen | Cadmium Chloride | Phenobarbital | sodium arsenite | Valproic Acid | Vitamin E 22.31 38
44. Birth Weight  
4 chemicals: Arsenic | Cadmium Chloride | Lead | Tetrachlorodibenzodioxin 22.02 6
45. Atrophy  
5 chemicals: Cadmium Chloride | cobaltous chloride | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid 21.50 11
46. Massive Hepatic Necrosis  
4 chemicals: Acetaminophen | Phenobarbital | pirinixic acid | Valproic Acid 21.50 2
47. Ovarian Diseases  
4 chemicals: Cadmium Chloride | 9,10-Dimethyl-1,2-benzanthracene | sodium arsenite | Tetrachlorodibenzodioxin 21.31 7
48. Drug-Related Side Effects and Adverse Reactions  
7 chemicals: Acetaminophen | Cadmium Chloride | Methylcholanthrene | Phenobarbital | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 21.07 26
49. Acute Kidney Injury  
7 chemicals: Acetaminophen | Cadmium Chloride | Copper Sulfate | Phenobarbital | pirinixic acid | sodium arsenite | Vitamin E 21.04 51
50. Anemia  
6 chemicals: Acetaminophen | Arsenic | sodium arsenite | Tetrachlorodibenzodioxin | Valproic Acid | Vitamin E 20.75 8
1–50 of 749 results.