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GO Term JAK-STAT cascade

Name JAK-STAT cascade
Exact Synonym JAK-STAT signal transduction
Definition Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The JAK-STAT cascade begins with activation of STAT proteins by members of the JAK family of tyrosine kinases, proceeds through dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.
Ontology Biological Process
GO ID GO:0007259
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Top ↑ Ancestors

1. ALLis a biological_process Has associated genes Has associated diseases is a response to stimulus Has associated genes Has associated diseases is a cellular response to stimulus Has associated genes Has associated diseases is a signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
2. ALLis a biological_process Has associated genes Has associated diseases is a cellular process Has associated genes Has associated diseases is a cellular response to stimulus Has associated genes Has associated diseases is a signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
3. ALLis a biological_process Has associated genes Has associated diseases is a single-organism process Has associated genes Has associated diseases is a single organism signaling Has associated genes Has associated diseases part of signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
4. ALLis a biological_process Has associated genes Has associated diseases is a signaling Has associated genes Has associated diseases is a single organism signaling Has associated genes Has associated diseases part of signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
5. ALLis a biological_process Has associated genes Has associated diseases is a cellular process Has associated genes Has associated diseases is a single-organism cellular process Has associated genes Has associated diseases is a cell communication Has associated genes Has associated diseases part of signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
6. ALLis a biological_process Has associated genes Has associated diseases is a single-organism process Has associated genes Has associated diseases is a single-organism cellular process Has associated genes Has associated diseases is a cell communication Has associated genes Has associated diseases part of signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
7. ALLis a biological_process Has associated genes Has associated diseases is a biological regulation Has associated genes Has associated diseases is a regulation of biological process Has associated genes Has associated diseases is a regulation of cellular process Has associated genes Has associated diseases is a signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
8. ALLis a biological_process Has associated genes Has associated diseases regulates regulation of biological process Has associated genes Has associated diseases is a regulation of cellular process Has associated genes Has associated diseases is a signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases
9. ALLis a biological_process Has associated genes Has associated diseases is a cellular process Has associated genes Has associated diseases regulates regulation of cellular process Has associated genes Has associated diseases is a signal transduction Has associated genes Has associated diseases is a intracellular signal transduction Has associated genes Has associated diseases is a JAK-STAT cascade Has associated genes Has associated diseases

Top ↑ Descendants

JAK-STAT cascade Has associated genes Has associated diseases
is a JAK-STAT cascade involved in growth hormone signaling pathway Has associated genes Has associated diseases
View nodenegatively regulates negative regulation of JAK-STAT cascade Has associated genes Has associated diseases
View nodepositively regulates positive regulation of JAK-STAT cascade Has associated genes Has associated diseases
View noderegulates regulation of JAK-STAT cascade Has associated genes Has associated diseases
View nodepart of STAT protein import into nucleus Has associated genes Has associated diseases
View nodepart of tyrosine phosphorylation of STAT protein Has associated genes Has associated diseases