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GO Term biological_process

These are exposure studies associated with the GO term and all of its children.

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1–50 of 580 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Lee DH, et al. (2007). National Health and Nutrition Examination Survey (NHANES) This study suggests that the prevalence of a cluster of cardiovascular risk factors relates to background exposure to a mixture of persistent organic pollutants, several of which are also related to the prevalence of diabetes. 1,2,3,4,6,7,8-heptachlorodibenzodioxin | 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Dibenzofurans, Polychlorinated | Hydrocarbons, Chlorinated | Pesticides | Polychlorinated Biphenyls | Polychlorinated Dibenzodioxins Study subjects United States Details Insulin Resistance | Metabolic Syndrome | cholesterol metabolic process | regulation of blood pressure | triglyceride metabolic process
2. Turyk ME, et al. (2007). National Health and Nutrition Examination Survey (NHANES) In the adult participants of NHANES from 1999 to 2002, total thyroxine was negatively associated with serum dioxin-like toxic equivalents in a dose-dependent fashion, with stronger associations in women than men. age | sex 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3,4,7,8-pentachlorodibenzofuran | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Benzofurans | dibenzodioxin | Dichlorodiphenyl Dichloroethylene | Dioxins and Dioxin-like Compounds | Hydrocarbons, Chlorinated | PCB 180 | Polychlorinated Biphenyls Study subjects United States serum 1,2,3,4,6,7,8-heptachlorodibenzofuran | 1,2,3,4,7,8-hexachlorodibenzofuran | 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3,4,7,8-pentachlorodibenzofuran | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 3,4,5,3',4',5'-hexachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Benzofurans | dibenzodioxin | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
3. Yang B, et al. (2016). Our results indicated polycyclic aromatic hydrocarbons exposure was associated with plasma cytokines, and higher cytokines were associated with decreased heart rate variability, but additional human and potential mechanistic studies are needed. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Workers China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | ALCAM | BDNF | CRP | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details Cardiovascular Diseases | gene expression
4. Li J, et al. (2018). Coke-oven Workers (COW) Cohort | Shiyan (SY) Cohort | Wuhan-Zhuhai (WHZH) Cohort Our findings suggest that exposure to polycyclic aromatic hydrocarbons may be associated with an adverse impact on human aging and epigenetic alterations in Chinese populations. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Study subjects China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details aging | DNA methylation
5. Deng Q, et al. (2014). Coke-oven Workers (COW) Cohort We identified five potentially polycyclic aromatic hydrocarbon (PAH)-associated miRNAs in plasma, and the same miRNAs were associated with a marker of chromosome damage in coke oven workers, suggesting that miRNAs might be a novel mechanism mediating the effects of PAH exposure on chromosome damage. alcohol drinking 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Workers China urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Details miRNA metabolic process
6. Barraza-Villarreal A, et al. (2014). Biomarkers of polycyclic aromatic hydrocarbons exposure were inversely associated with lung function and decrease of pH of exhaled breath condensate as a marker of airway inflammation in Mexican schoolchildren. 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Fluorenes | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Children Mexico urine 1-hydroxyphenanthrene | 1-hydroxypyrene | 1-naphthol | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | fluoren-9-ol | Fluorenes | Phenanthrenes Details respiratory system process
7. Zhou Y, et al. (2016). Wuhan-Zhuhai (WHZH) Cohort Total and specific urinary polycyclic aromatic hydrocarbons metabolites were associated with lung function reduction in a general Chinese population. 1-hydroxyphenanthrene | 1-hydroxypyrene | 2-hydroxyfluorene | 2-naphthol | 4-hydroxyphenanthrene | 9-phenanthrol | fluoren-9-ol | Phenanthrenes | Polycyclic Aromatic Hydrocarbons Study subjects China urine Polycyclic Aromatic Hydrocarbons Details respiratory system process
8. Meeker JD, et al. (2004). In the present study we found associations between urinary metabolites of contemporary-use insecticides and decreased sperm concentration and motility in humans. 1-naphthol | 3,5,6-trichloro-2-pyridinol | Insecticides Subjects with disease:Infertility, Male United States semen | urine 1-naphthol | 3,5,6-trichloro-2-pyridinol Details Infertility, Male | spermatogenesis | sperm motility
9. Eskenazi B, et al. (2018). Venda Health Examination of Mothers, Babies and the Environment (VHEMBE) Study Prenatal exposure to pyrethroids may be associated at 1 y of age with poorer social-emotional development. At 2 y of age, poorer language development was observed with higher prenatal pyrethroid levels. 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene | 3-phenoxybenzoic acid | DDT | Dichlorodiphenyl Dichloroethylene | o,p'-DDT | Pyrethrins Children | Pregnant females South Africa serum | urine 2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene | 3-phenoxybenzoic acid | DDT | Dichlorodiphenyl Dichloroethylene | o,p'-DDT | Pyrethrins Details cognition | motor behavior | social behavior
10. Kobayashi S, et al. (2017). Hokkaido Birth Cohort Study on Environment and Children's Health Our results suggest that the dose-dependent association between prenatal exposure to specific non-dioxin-like polychlorinated biphenyls and increases in the H19 and LINE-1 methylation levels in cord blood might be more predominant in females than in males. sex 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3,3',4,6'-hexachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,4',5',6-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',3,5',6-pentachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | decachlorobiphenyl | PCB 180 | Polychlorinated Biphenyls Infants or newborns | Pregnant females Japan blood 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3,3',4,6'-hexachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,4',5',6-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',3,5',6-pentachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | decachlorobiphenyl | PCB 180 | Polychlorinated Biphenyls Details methylation
11. Robledo CA, et al. (2015). Longitudinal Investigation of Fertility and the Environment Study (LIFE) Preconceptional maternal and paternal concentrations of several persistent organic pollutants were associated with statistically significant differences in birth size among offspring. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Fluorocarbons | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hexachlorocyclohexane | hexadecafluoro-nonanoic acid | Mirex | N-ethyl perfluorooctane sulfonamido acetate | nonachlor | o,p'-DDT | oxychlordane | PBB 153 | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Infants or newborns | Mothers | Study subjects United States serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Fluorocarbons | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hexachlorocyclohexane | hexadecafluoro-nonanoic acid | Mirex | N-ethyl perfluorooctane sulfonamido acetate | nonachlor | o,p'-DDT | oxychlordane | PBB 153 | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorodecanoic acid | perfluorooctanesulfonamide | perfluorooctane sulfonic acid | perfluorooctanoic acid | Polychlorinated Biphenyls | tribromodiphenyl ether 28 Details Prenatal Exposure Delayed Effects | developmental growth | head development
12. Schell LM, et al. (2009). Mohawk Adolescent Well-Being Study (MAWBs) Our results show that the groups of more persistent Polychlorinated biphenyls (PCBs) are unambiguously associated with an elevated thyroid peroxidase antibody level among late teens and young adults who had been breast fed as infants. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5',6-pentachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | PCB 180 | Polychlorinated Biphenyls Study subjects United States blood 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5',6-pentachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,4'5-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mirex | PCB 180 Details production of molecular mediator of immune response
13. Takser L, et al. (2005). These results suggest that at even low levels of exposure, persistent environmental contaminants can interfere with thyroid status during pregnancy. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Aldrin | beta-hexachlorocyclohexane | Chlordan | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mercury | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Infants or newborns | Mothers Canada blood, cord | plasma 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Aldrin | beta-hexachlorocyclohexane | Chlordan | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mercury | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Details thyroid hormone metabolic process
14. Goncharov A, et al. (2008). High serum polychlorinated biphenyls are associated with elevation of serum lipids and cardiovascular disease in a Native American population. age 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mirex | PCB 180 | Polychlorinated Biphenyls Study subjects Canada|United States serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Mirex | PCB 180 | Polychlorinated Biphenyls Details Cardiovascular Diseases | cholesterol biosynthetic process | triglyceride biosynthetic process
15. Vested A, et al. (2014). The objective of this study was to investigate whether maternal serum concentrations of polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) during pregnancy are associated with son's semen quality and reproductive hormone levels. 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Mothers | Study subjects Denmark semen | serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Estradiol | FSHB | INHBB | LHB | PCB 180 | SHBG | Testosterone Details spermatogenesis | sperm motility
16. Fitzgerald EF, et al. (2008). The results suggest that exposure to Polychlorinated biphenyls may be associated with some measures of memory and learning and depression among adults 55-74 years of age whose current body burdens are similar to those of the general population. age | sex 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | DDT | Dichlorodiphenyl Dichloroethylene | Lead | Mercury | PCB 180 | Polychlorinated Biphenyls Study subjects United States blood | serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Lead | Mercury | PCB 180 | Polychlorinated Biphenyls Details Depressive Disorder | cognition
17. Patel CJ, et al. (2012). National Health and Nutrition Examination Survey (NHANES) We screened for correlation between environmental factors and lipid levels, utilizing four independent surveys with information on 188 environmental factors from the Centers of Disease Control, National Health and Nutrition Examination Survey, collected between 1999 and 2006. age | body mass index | race | sex | socioeconomic status 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2,4,4',5-tetrachlorobiphenyl | 2-hydroxyfluorene | alpha-Tocopherol | Ascorbic Acid | beta Carotene | Cotinine | Cryptoxanthins | Fluorenes | Folic Acid | gamma-Tocopherol | Heptachlor Epoxide | Iron | Lycopene | Mercury | nonachlor | oxychlordane | retinol palmitate | retinyl stearate | Vitamin A | Vitamin D Study subjects United States Details cholesterol metabolic process | triglyceride metabolic process
18. Park SY, et al. (2015). In this study, we explored whether low dose organochlorine pesticides and polychlorinated biphenyls were associated with promoter methylation of the MGMT gene in peripheral leukocytes among persons without overt cancer. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,4',5,5',6-heptachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,3',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Heptachlor Epoxide | Hexachlorobenzene | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Study subjects Korea, Republic of serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,4',5,5',6-heptachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,3',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Heptachlor Epoxide | Hexachlorobenzene | Mirex | nonachlor | oxychlordane | PCB 180 | Polychlorinated Biphenyls Details hypermethylation of CpG island
19. Herbstman JB, et al. (2008). Prenatal polychlorinated biphenyls (PCBs) and poly-brominated diphenyl ether (PBDE) exposures were associated with reduced total thyroxine and free thyroxine levels among infants born by spontaneous, unassisted vaginal delivery. Intrapartum stress associated with delivery mode may mask hormonal effects of PCBs and PBDEs. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Halogenated Diphenyl Ethers | PCB 180 | pentabromodiphenyl ether | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Infants or newborns United States blood | blood, cord 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | PCB 180 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls | Thyrotropin | Thyroxine Details thyroid hormone metabolic process
20. Kim KY, et al. (2010). We found that low-dose exposure to persistent organic pollutants, in particular organochlorine pesticides, was associated with global DNA hypomethylation in apparently healthy Koreans. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyldichloroethane | Dichlorodiphenyl Dichloroethylene | Heptachlor Epoxide | Hexachlorobenzene | Mirex | nonachlor | oxychlordane | PCB 180 Study subjects Korea, Republic of serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyldichloroethane | Dichlorodiphenyl Dichloroethylene | Heptachlor Epoxide | Hexachlorobenzene | Mirex | nonachlor | oxychlordane | PCB 180 Details DNA methylation
21. Dallaire R, et al. (2009). Exposure to several polyhalogenated compounds was associated with modifications of the thyroid parameters in adult Inuit, mainly by reducing total triiodothyronine and thyroxine-binding globulin circulating concentrations. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Dioxins | Halogenated Diphenyl Ethers | Hexachlorobenzene | Hydrocarbons, Chlorinated | PCB 180 | Pentachlorophenol | perfluorooctane sulfonic acid | Polybrominated Biphenyls | Polychlorinated Biphenyls | Selenium Study subjects Canada blood | plasma | serum 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | Dioxins | hexabrominated diphenyl ether 153 | Hexachlorobenzene | PCB 180 | Pentachlorophenol | perfluorooctane sulfonic acid | Polychlorinated Biphenyls | Selenium | SERPINA7 | Thyroxine | Triiodothyronine | TSHB Details regulation of thyroid-stimulating hormone secretion | thyroid hormone metabolic process
22. Chevrier J, et al. (2007). Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) In summary, we report a positive association between neonatal thyroid-stimulating hormone levels and prenatal exposure to polychlorinated biphenyls (PCBs) reported to induce microsomal enzymes (specifically CYP2B) and suspected to induce uridinediphosphate glucuronosyltransferase in animals but not with the sum of all PCB congeners, or PCBs grouped according to their dioxin-like activity or structure. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | PCB 180 | Polycyclic Aromatic Hydrocarbons Pregnant females United States serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-pentachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | PCB 180 | Polycyclic Aromatic Hydrocarbons Details hormone metabolic process
23. Glynn A, et al. (2008). This hypothesis generating study suggests that background exposure to polychlorinated biphenyls and Dichlorodiphenyl Dichloroethylene early in life modulate immune system development. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Infants or newborns | Mothers | Pregnant females Sweden milk, human | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 Details Respiratory Tract Infections | immune system development
24. Perry MJ, et al. (2016). Organochlorine exposures measured at age 14 and in adulthood were associated with sperm disomy in this sample of high-exposure men, suggesting that the impacts of persistent pollutants on testicular maturation and function require further investigation. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 Children | Infants or newborns | Study subjects Faroe Islands blood, cord | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Details Aneuploidy | male meiosis chromosome separation
25. Hauser R, et al. (2003). To explore the hypothesis that environmental exposures to polychlorinated biphenyls and dichlorodiphenyldichloroethylene are associated with altered semen parameters, we conducted a cross-sectional study of 212 male partners of subfertile couples who presented to the Massachusetts General Hospital Andrology Laboratory. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Polychlorinated Biphenyls Study subjects United States serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Polychlorinated Biphenyls Details spermatogenesis | sperm motility
26. Park SH, et al. (2016). Ewha Birth & Growth Cohort Study The results of the study suggested that exposure to persistent organic pollutants among children might affect insulin secretory function, which could lead to an increased risk of developing diabetes. 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | nonachlor | PCB 180 | Polychlorinated Biphenyls Children Korea, Republic of serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | Dichlorodiphenyl Dichloroethylene | nonachlor | PCB 180 | Polychlorinated Biphenyls Details Diabetes Mellitus | insulin secretion
27. Valvi D, et al. (2014). INfancia y Medio Ambiente (INMA) Project We found that prenatal exposure to dichlorodiphenyldichloroethylene and hexachlorobenzene is associated with rapid growth in the first 6 months of life and subsequent overweight at 14 months of age. 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | PCB 180 | Polychlorinated Biphenyls Infants or newborns | Pregnant females Spain serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | PCB 180 | Polychlorinated Biphenyls Details Overweight | growth
28. Daniel V, et al. (2001). Exposure to industrial chemicals is associated with only weak immunologic abnormalities; these results contrast with those obtained in earlier studies which showed a strong dose-dependent relationship with immunologic impairments; our data suggest that long-term exposure of patients to hexachlorobenzene suppresses interferon-gamma production. 2,2',3',4,4',5-hexachlorobiphenyl | beta-hexachlorocyclohexane | Hexachlorobenzene | Hexachlorocyclohexane | Polychlorinated Biphenyls Workers Germany blood | plasma 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | beta-hexachlorocyclohexane | Hexachlorobenzene | Hexachlorocyclohexane | IFNG | IL4 | PCB 180 Details interferon-gamma production | interleukin-4 production | T-helper 1 cell cytokine production
29. Clair HB, et al. (2018). Anniston Community Health Survey (ACHS) Toxicant-associated steatohepatitis was associated with increased exposures to specific PCB congeners, and the sum of PCBs had associations with insulin, leptin, adipocytokines, and hepatocyte apoptosis. 2,2',3,5,5',6-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | Polychlorinated Biphenyls Subjects with disease:Fatty Liver | Subjects with disease:Liver Diseases | Study subjects United States serum 2,2',3,4',5',6-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,3,4,2',3',4'-hexachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | ADIPOQ | IL1B | IL6 | INS | KRT18 | LEP | SERPINE1 | TNF Details Fatty Liver | positive regulation of cell death | regulation of apoptotic process
30. Dao T, et al. (2015). Boston Birth Cohort (BBC) Our results suggested that maternal PBDE47 exposure altered CpG site specific DNA methylation at the TNF-alpha promoter, which may contribute to the aberrant TNF-alpha gene expression in the offspring. sex 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | tribromodiphenyl ether 28 Infants or newborns | Pregnant females United States blood, cord | serum 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | tribromodiphenyl ether 28 Details DNA methylation | gene expression
31. Eggesbø M, et al. (2011). Norwegian Human Milk Study (HUMIS) The present study did not find any associations between the levels of brominated flame retardants measured in human milk and thyroid-stimulating hormone levels in newborns. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | decabromobiphenyl ether | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | hexabromocyclododecane | hexabromodiphenyl ether 154 Infants or newborns | Mothers Norway milk, human 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | decabromobiphenyl ether | hexabrominated diphenyl ether 153 | hexabromocyclododecane | hexabromodiphenyl ether 154 Details thyroid-stimulating hormone secretion
32. Turyk ME, et al. (2008). Consortium for the health assessment of Great Lakes sport fish consumption Polychlorinated biphenyls exposure, at levels comparable with those of the general U.S. population, was associated with increased thyroglobulin antibodies and increased T(4) in adult males. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls Study subjects United States serum | urine 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | Polychlorinated Biphenyls | SERPINA7 | Testosterone | Thyrotropin | Thyroxine | Triiodothyronine Details immunoglobulin production | testosterone biosynthetic process | thyroid hormone metabolic process
33. Makey CM, et al. (2016). Our findings suggest that polybrominated diphenyl ether exposure might decrease the binding of thyroxine (T4) to serum T4 binding proteins. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | perchlorate | thiocyanate | Thyroxine | tribromodiphenyl ether 28 Workers United States serum | urine 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | Iodine | Lipids | pentabrominated diphenyl ether 100 | perchlorate | thiocyanate | Thyroxine | tribromodiphenyl ether 28 | Triiodothyronine | TSHB Details thyroid hormone metabolic process
34. Miranda ML, et al. (2015). Children's Environmental Health Initiative Healthy Pregnancy, Healthy Baby Our data suggest a potential association between maternal polybrominated diphenyl ether levels and decreased infant head circumference (however, this association was attenuated after control for maternal risk factors); confirmatory studies are needed in larger sample sizes, and a mediating role of thyroid hormones was not apparent. 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | Halogenated Diphenyl Ethers | hexabrominated diphenyl ether 153 | Polybrominated Biphenyls Infants or newborns | Pregnant females United States serum 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,6-tribromophenol | 6-OH-BDE-47 | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | pentabrominated diphenyl ether 100 | Thyroxine | tribromodiphenyl ether 28 | Triiodothyronine | TSHB Details Prenatal Exposure Delayed Effects | head development
35. Hoffman K, et al. (2016). Pregnancy Infection and Nutrition (PIN) Study We prospectively investigate the association between early-life exposure to polybrominated diphenyl ethers through breast milk and early childhood weight-for age, height-for-age, and weight-for-height in a cohort of central North Carolina children. sex 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | tribromodiphenyl ether 28 Infants or newborns | Mothers United States milk, human 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | hexabrominated diphenyl ether 153 | pentabrominated diphenyl ether 100 | tribromodiphenyl ether 28 Details regulation of developmental growth
36. Leijs MM, et al. (2012). Thyroid hormone metabolism seems to have been influenced by current background levels of the common environmental contaminants dioxin like-polychlorinated biphenyls and BDE-99 (2,2',4,4',5-brominated diphenyl ether). 2,2',4,4',5-brominated diphenyl ether | Polychlorinated Biphenyls Study subjects Netherlands serum Triiodothyronine Details thyroid hormone metabolic process
37. Béranger R, et al. (2016). PELAGIE Prenatal urine concentrations of two glycol ethers metabolites were associated with lower Wechsler Intelligence Scale for Children IV Verbal Comprehension Index scores and Developmental Neuropsychological Assessment Design Copying subscale scores, respectively, at age six. 2-(2-methoxyethoxy)ethanol | carbitol | Ethylene Glycols | n-butoxyacetic acid | phenoxyethanol Children | Pregnant females France urine carbitol | ethoxyacetic acid | methoxyacetic acid | n-butoxyacetic acid | phenoxyacetic acid Details cognition | visual learning
38. Paunescu AC, et al. (2013). Nituuchischaayihtitaau Aschii Multi-community Environment- and Health Longitudinal Study in Eeyou Istchee Our results show that an increase in plasma concentrations of dioxin-like polychlorinated biphenyls 105 and 118 was negatively associated with stiffness index, a measure of bone quality-strength, in women of this population. 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | Dioxins and Dioxin-like Compounds | Lead | Mercury | Selenium Study subjects Canada blood | plasma 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | Dioxins and Dioxin-like Compounds | Lead | Mercury | Selenium Details Osteoporosis | regulation of bone mineralization
39. Park HY, et al. (2010). Children with higher prenatal mono-ortho-substituted polychlorinated biphenyl exposures performed more poorly on the Bayley Scales. Evidence from this and other studies suggests that prenatal dioxin-like PCB exposure, including mono-ortho congeners, may interfere with brain development in utero. 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | Polychlorinated Biphenyls Children | Infants or newborns | Mothers Slovakia serum | serum, cord 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | Polychlorinated Biphenyls Details cognition
40. Turyk M, et al. (2009). Consortium for the health assessment of Great Lakes sport fish consumption This study demonstrates an association between p,p'-diphenyldichloroethene exposure and incident diabetes. 2,3',4,4',5-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Polychlorinated Biphenyls Controls for disease:Diabetes Mellitus | Subjects with disease:Diabetes Mellitus | Study subjects United States serum 2,3',4,4',5-pentachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Polychlorinated Biphenyls Details Diabetes Mellitus | glucose homeostasis
41. Toft G, et al. (2005). We observed regional differences in time to pregnancy and sperm motility that may be related to regional differences in POP blood levels, but other interpretations are also plausible. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Study subjects Greenland|Poland|
Sweden|Ukraine
serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details sperm motility
42. Jusko TA, et al. (2016). The results from this prospective birth cohort study suggest that two common environmental contaminants, PCB-153 and p,p'-DDE, substantially reduce the infant response to Mycobacterium bovis bacille Calmette-Guerin (BCG) vaccination. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Infants or newborns | Pregnant females Slovakia blood, cord | serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details IgA receptor activity | IgG receptor activity | immune response
43. Iszatt N, et al. (2015). Flemish Environment and Health Survey (FLEHS I) | Groningen-Rotterdam-Dusseldorf Cohort | Growing up in France (ELFE) | Michalovce Cohort | Norwegian Human Milk Study (HUMIS) | PELAGIE We found that prenatal p,p'-DDE exposure was significantly associated with increased infant growth, and postnatal PCB-153 exposure with decreased infant growth. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Infants or newborns Belgium|France|
Germany|Netherlands|
Slovakia
2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details developmental growth
44. Rignell-Hydbom A, et al. (2005). The main result of the present study was a positive association between serum levels of 2,2',4,4',5,5'-hexachlorobiphenyl and %DNA fragmentation index, indicating that persistent organochlorine pollutant exposure might affect sperm DNA integrity. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Workers Sweden serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details chromatin maintenance | spermatogenesis
45. Høyer BB, et al. (2015). INUENDO In utero exposure to 2,2',4,4',5,5'-hexachlorobiphenyl and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene was not associated with parentally retrospectively assessed developmental milestones in infancy or parentally assessed motor skills at young school age. 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Children | Pregnant females Greenland|Poland|
Ukraine
serum 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details locomotory behavior
46. Dallaire R, et al. (2009). In this study we examined the relationship between exposure to potential thyroid hormone-disrupting toxicants and thyroid hormone status in pregnant Inuit women from Nunavik and their infants within the first year of life. 2,4,5,2',4',5'-hexachlorobiphenyl | Hexachlorobenzene | Pentachlorophenol | Polychlorinated Biphenyls Infants or newborns | Pregnant females Canada blood, cord | plasma 2,4,5,2',4',5'-hexachlorobiphenyl | Hexachlorobenzene | Pentachlorophenol | Polychlorinated Biphenyls Details gene expression | hormone metabolic process
47. LaRocca J, et al. (2015). Harvard Epigenetic Birth Cohort (HEBC) These results suggest that prenatal phenol and phthalate exposure is associated with altered microRNA expression in placenta, suggesting a potential mechanism of endocrine-disrupting chemicals toxicity in humans. 2,4-dichlorophenol | 2,5-dichlorophenol | bisphenol A | butylbenzyl phthalate | butylparaben | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisodecyl phthalate | diisononyl phthalate | methylparaben | oxybenzone | Parabens | Phenols | Phthalic Acids | propylparaben | Triclosan Infants or newborns | Pregnant females United States placenta | urine 2,4-dichlorophenol | 2,5-dichlorophenol | 2-ethyl-5-carboxypentyl phthalate | bisphenol A | butylparaben | diisodecyl phthalate | diisononyl phthalate | methylparaben | MIR142 | MIR15A | MIR185 | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | oxybenzone | propylparaben | Triclosan Details regulation of gene silencing by miRNA
48. Schreinemachers DM. (2010). National Health and Nutrition Examination Survey (NHANES) The results indicate that exposure to 2,4-dichlorophenoxyacetic acid was associated with changes in biomarkers that, based on the published literature, have been linked to risk factors for acute myocardial infarction and type 2 diabetes. 2,4-Dichlorophenoxyacetic Acid Study subjects United States urine 2,4-Dichlorophenoxyacetic Acid Details Diabetes Mellitus, Type 2 | Heart Diseases | cellular triglyceride homeostasis | glucose metabolic process | insulin metabolic process | thyroid-stimulating hormone secretion
49. Andreotti G, et al. (2014). Agricultural Health Study (AHS) We found two herbicides (alachlor and 2,4-dichlorophenoxyacetic acid) and two insecticides (diazinon and aldrin) significantly associated with alterations in relative telomere length in blood DNA. 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldrin | Diazinon Workers United States Details telomere maintenance
50. Hou L, et al. (2013). Agricultural Health Study (AHS) Seven pesticides previously associated with cancer risk in the epidemiologic literature were inversely associated with relative telomere length in buccal cell DNA among cancer-free pesticide applicators. age 2,4-Dichlorophenoxyacetic Acid | alachlor | DDT | metolachlor | Permethrin | Toxaphene | Trifluralin Workers United States Details telomere maintenance
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