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GO Term aminoacyl-tRNA synthetase multienzyme complex

Name aminoacyl-tRNA synthetase multienzyme complex
Exact Synonyms aminoacyl-tRNA synthetase complex | multisynthetase complex
Definition A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.
Ontology Cellular Component
GO ID GO:0017101
External Links

Top ↑ Ancestors

1. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a aminoacyl-tRNA synthetase multienzyme complex Has associated genes Has associated diseases
2. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a aminoacyl-tRNA synthetase multienzyme complex Has associated genes Has associated diseases
3. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a aminoacyl-tRNA synthetase multienzyme complex Has associated genes Has associated diseases
4. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a aminoacyl-tRNA synthetase multienzyme complex Has associated genes Has associated diseases
5. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a protein-containing complex Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a aminoacyl-tRNA synthetase multienzyme complex Has associated genes Has associated diseases

Top ↑ Descendants

None.