Skip navigation

GO Term ubiquitin activating enzyme complex

Name ubiquitin activating enzyme complex
Exact Synonym E1 complex
Related Synonym E1 ubiquitin-activating enzyme
Definition A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP-->E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
Ontology Cellular Component
GO ID GO:0120123
External Links

Top ↑ Ancestors

1. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a protein-containing complex Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a catalytic complex Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a ubiquitin activating enzyme complex
2. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a ubiquitin activating enzyme complex
3. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a ubiquitin activating enzyme complex
4. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a ubiquitin activating enzyme complex
5. ALLis a cellular_component Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a cell Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of cell part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a intracellular Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references part of intracellular part Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references is a ubiquitin activating enzyme complex

Top ↑ Descendants

None.