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Comparative Toxicogenomics Database

This chemical–disease association may be inferred in part via curated interactions between Aluminum and any genes listed below, and a curated association between those genes and Status Epilepticus.

		Reference	Association
1.		Lively S, et al. Induction of heat shock proteins in the adult rat cerebral cortex following pilocarpine-induced status epilepticus. Brain Res. 2011 Jan 12;1368:271-80.	Inferred via 1 gene: HMOX1
2.		Liu J, et al. Oxidative stress mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus. Seizure. 2010 Apr;19(3):165-72.	Inferred via 2 genes: NOS1 | NOS2
3.		Martinez Y, et al. Blockade of the sodium calcium exchanger exhibits anticonvulsant activity in a pilocarpine model of acute seizures in rats. Brain Res. 2010 Dec 17;1366:211-6.	Inferred via 1 gene: SLC8A3
4.		Persike DS, et al. Protective effect of the organotelluroxetane RF-07 in pilocarpine-induced status epilepticus. Neurobiol Dis. 2008 Jul;31(1):120-6.	Inferred via 1 gene: CASP3
5.		Santos LF, et al. Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures. Pharmacol Biochem Behav. 2008 Mar;89(1):1-5.	Inferred via 1 gene: CAT
6.		Scorza CA, et al. Myocyte-specific enhancer binding factor 2C (MEF2C) expression in the dentate gyrus during development and after pilocarpine-induced status epilepticus: a preliminary report. Arq Neuropsiquiatr. 2008 Sep;66(3B):731-5.	Inferred via 1 gene: MEF2C
7.		Sun H, et al. Peroxisome proliferator-activated receptor gamma agonist, rosiglitazone, suppresses CD40 expression and attenuates inflammatory responses after lithium pilocarpine-induced status epilepticus in rats. Int J Dev Neurosci. 2008 Aug;26(5):505-15.	Inferred via 1 gene: TNF
8.		Zhang HJ, et al. Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats. J Zhejiang Univ Sci B. 2008 Nov;9(11):903-15.	Inferred via 1 gene: PTGS2
9.		Barros DO, et al. Effects of the vitamin E in catalase activities in hippocampus after status epilepticus induced by pilocarpine in Wistar rats. Neurosci Lett. 2007 Apr 18;416(3):227-30.	Inferred via 1 gene: CAT
10.		Wen X, et al. Erythropoietin preconditioning on hippocampus neuronal apoptosis following status epilepticus induced by Li-pilocarpine in rats through anti-caspase-3 expression. Neurol India. 2006 Mar;54(1):58-63; discussion 63.	Inferred via 1 gene: CASP3
11.		Freitas RM, et al. Oxidative stress in the hippocampus after pilocarpine-induced status epilepticus in Wistar rats. FEBS J. 2005 Mar;272(6):1307-12.	Inferred via 1 gene: CAT
12.		Freitas RM, et al. Catalase activity in cerebellum, hippocampus, frontal cortex and striatum after status epilepticus induced by pilocarpine in Wistar rats. Neurosci Lett. 2004 Jul 22;365(2):102-5.	Inferred via 1 gene: CAT
13.		Williams MB, et al. Distinctive rat brain immediate early gene responses to seizures induced by lithium plus pilocarpine. Brain Res Mol Brain Res. 1994 Aug;25(1-2):80-9.	Inferred via 1 gene: JUN