| 1. |
Aluminum
|
Alzheimer Disease
|
M |
|
20 genes: ABCA7 | ACE | APP | BAX | CASP3 | ESR1 | F2 | HMOX1 | IDE | IGF1 | IL1B | MAPT | MPO | NPY | PICALM | PYY | SLC30A4 | SOD2 | TF | TNF
|
12.20 |
49 |
| 2. |
Aluminum
|
Poisoning
|
M |
|
2 genes: ACHE | SLC22A2
|
7.37 |
7 |
| 3. |
Aluminum
|
Nerve Degeneration
|
M |
|
24 genes: AGTPBP1 | APP | ATXN3 | BAX | CASP3 | CDH1 | CNTF | EPOR | F2 | IGF1 | KCNJ6 | MAPK3 | NGFR | NOS1 | OTX2 | SEPP1 | SKN-1 | SLC1A2 | SLC6A3 | SMF-3 | SNCA | SOD2 | TNF | XDH
|
6.16 |
35 |
| 4. |
Aluminum
|
Brain Diseases
|
M |
|
2 genes: ALB | APP
|
5.80 |
5 |
| 5. |
Aluminum
|
Lung Diseases
|
M |
|
12 genes: ACE | CLEC4E | HIF1A | IRX1 | IRX2 | IRX3 | KIT | PTGS2 | PTH1R | PTHLH | SCGB1A1 | TNF
|
4.89 |
9 |
| 6. |
Aluminum
|
Neurodegenerative Diseases
|
M |
|
9 genes: APOD | APP | CRYAB | HMOX1 | MAPT | NGFR | SEPP1 | SNCA | SOD2
|
4.83 |
12 |
| 7. |
Aluminum
|
Amyotrophic Lateral Sclerosis
|
M |
|
5 genes: GFAP | PLA2G4A | PTGS2 | SLC1A2 | UNC13A
|
4.11 |
5 |
| 8. |
Aluminum
|
Dyslipidemias
|
M |
|
1 gene: APOB
|
3.84 |
2 |
| 9. |
Aluminum
|
Memory Disorders
|
M |
|
6 genes: ACHE | APP | IL1B | MAPT | NPY | SLC6A3
|
3.80 |
12 |
| 10. |
Aluminum
|
Neoplasms
|
M |
|
8 genes: CAT | IL18 | IL2 | LTF | NAT1 | PTGS2 | SOD2 | VDR
|
3.70 |
14 |
| 11. |
Aluminum
|
Anemia
|
M |
|
6 genes: IFNA2 | IL2 | IL3 | PTH | SOD2 | TNF
|
3.50 |
13 |
| 12. |
Aluminum
|
Neurotoxicity Syndromes
|
M |
|
4 genes: ALOX5AP | CASP3 | CD3D | RNASE6
|
3.30 |
3 |
| 13. |
Aluminum
|
Fragile X Syndrome
|
M |
|
1 gene: APP
|
3.16 |
2 |
| 14. |
Aluminum
|
Bronchial Hyperreactivity
|
M |
|
2 genes: IL13 | TRPA1
|
3.00 |
3 |
| 15. |
Aluminum
|
Inflammation
|
M |
|
16 genes: ADIPOQ | BDKRB2 | HMOX1 | IL1B | LTF | MPO | NOS2 | PTGS2 | SCGB1A1 | SLC22A5 | TF | TFRC | TLR2 | TNF | TRPA1 | ZFP36
|
2.77 |
32 |
| 16. |
Aluminum
|
Nervous System Diseases
|
M |
|
12 genes: ACHE | CASP3 | EN1 | GFAP | ID3 | NFATC2 | NOS1 | PTGS2 | SEPP1 | SLC19A1 | SLC6A3 | TNF
|
2.19 |
16 |
| 17. |
Aluminum
|
Parkinson Disease
|
M |
|
9 genes: DRD2 | GFAP | GPX1 | HMOX1 | MAPT | SLC6A3 | SNCA | SOD2 | TNF
|
2.09 |
31 |
| 18. |
Aluminum
|
Diabetes Complications
|
M |
|
|
|
1 |
| 19. |
Aluminum
|
Epilepsy, Tonic-Clonic
|
M |
|
|
|
1 |
| 20. |
Aluminum
|
Eye Diseases
|
M |
|
|
|
1 |
| 21. |
Aluminum
|
Granuloma
|
M |
|
|
|
1 |
| 22. |
Aluminum
|
Heavy Metal Toxicity
|
M |
|
|
|
1 |
| 23. |
Aluminum
|
Lymphadenitis
|
M |
|
|
|
1 |
| 24. |
Aluminum
|
Multiple Sclerosis, Chronic Progressive
|
M |
|
|
|
1 |
| 25. |
Aluminum
|
Multiple Sclerosis, Relapsing-Remitting
|
M |
|
|
|
1 |
| 26. |
Aluminum
|
Osteomalacia
|
M |
|
|
|
1 |
| 27. |
Aluminum
|
Renal Osteodystrophy
|
M |
|
|
|
1 |
| 28. |
Aluminum
|
Autistic Disorder
|
|
|
36 genes: ADM | AR | CACNA1H | CAT | GPX1 | HDLBP | HOXD11 | HTR1B | HTR1D | HTR5A | IGF1 | IL13 | IL15 | IL2 | IL4 | IL5 | LASP1 | MEF2C | NF1 | NOS2 | NRXN1 | PDE4B | PECAM1 | PIK3CG | PLA2G4A | PRKCB | PTGS2 | ROBO2 | SHANK2 | SLC19A1 | SLC1A3 | SLC6A8 | TDO2 | TF | TNFRSF1B | XDH
|
18.78 |
38 |
| 29. |
Aluminum
|
Obesity
|
|
|
28 genes: ACLY | ADH1B | ADIPOQ | ADRB1 | AKAP1 | CES1 | CPB2 | CTF1 | CTSS | ESR1 | GNPDA2 | GPX1 | HMOX1 | HOXB5 | MMP9 | NHLH2 | NPY5R | PACS1 | PCSK1 | PTGS2 | PYY | SIM1 | SOD2 | TF | TFRC | TNF | TNFRSF1B | UCP1
|
17.76 |
28 |
| 30. |
Aluminum
|
Nausea
|
|
|
2 genes: IFNA2 | TNF
|
13.14 |
4 |
| 31. |
Aluminum
|
Arthritis, Rheumatoid
|
|
|
23 genes: ADIPOQ | BAIAP2L1 | BDKRB2 | BLK | CAT | CD3E | CD5 | CXCL6 | HOXD11 | HOXD13 | IL18 | IL1B | MMP2 | MPO | POU3F1 | PRDM1 | PTGS2 | PTPN22 | PTPRC | RGMB | SOD2 | TAGAP | TNF
|
12.46 |
15 |
| 32. |
Aluminum
|
Vomiting
|
|
|
2 genes: GNRH1 | IFNA2
|
12.25 |
3 |
| 33. |
Aluminum
|
Peripheral Nervous System Diseases
|
|
|
41 genes: ABCA1 | AICDA | ALDH1A1 | APOB | ARSA | BAX | CEP250 | CES1 | DBH | ESR1 | FMO3 | GFAP | GPR15 | GPX1 | GZMH | ID3 | IFNA1 | IGF1 | IL18 | IL2 | IL3 | JUN | MN1 | MTR | NAT1 | NEFH | NEK4 | NPY | PIK3CG | PLXDC2 | PRKCE | PTGIS | SIM1 | SLC22A5 | SLC22A8 | SOD2 | TLN2 | TNF | TNFSF8 | UCP1 | WNT11
|
12.06 |
7 |
| 34. |
Aluminum
|
Seizures
|
|
|
18 genes: ACHE | ALAD | CAT | CHAT | DRD1A | DRD2 | GRIK1 | HTR1B | IL1B | NGFR | NOS1 | NOS2 | NPY | OPRM1 | PTGS2 | SLC2A1 | SLC8A3 | SOD2
|
11.84 |
26 |
| 35. |
Aluminum
|
Headache
|
|
|
2 genes: GNRH1 | IFNA2
|
11.75 |
2 |
| 36. |
fluoroaluminum
|
Carcinoma, Hepatocellular
|
|
|
3 genes: ABCB1 | IGF2 | PTK2
|
11.57 |
4 |
| 37. |
Aluminum
|
Radiation Injuries, Experimental
|
|
|
6 genes: IL18 | IL1B | MAPK3 | NOS1 | SOD2 | TNF
|
11.52 |
3 |
| 38. |
Aluminum
|
Catalepsy
|
|
|
2 genes: DRD1A | DRD2
|
11.39 |
4 |
| 39. |
Aluminum
|
Necrosis
|
|
|
8 genes: APP | ATG7 | CAT | CTF1 | IL1B | NOS2 | SOD2 | TNF
|
10.92 |
11 |
| 40. |
Aluminum
|
Bradycardia
|
|
|
4 genes: CHRM2 | DRD2 | GNAI2 | GNRH1
|
10.64 |
5 |
| 41. |
Aluminum
|
Calcinosis
|
|
|
10 genes: AHSG | BGLAP | C6 | CASP3 | IL18 | IL1B | LY86 | MMP2 | MMP9 | PYCARD
|
10.24 |
4 |
| 42. |
Aluminum
|
Amphetamine-Related Disorders
|
|
|
16 genes: ACHE | DRD1A | DRD2 | GABRG2 | HTR1B | MAP2K5 | MARC1 | NOS1 | OPRM1 | PDE4B | POU5F1 | PRKG1 | PSD3 | RAPGEF5 | SLC6A3 | SNCA
|
9.70 |
12 |
| 43. |
Aluminum
|
Pain
|
|
|
9 genes: ADM | ALB | BDKRB2 | DRD2 | HRH1 | IFNA2 | IL2 | TNF | TRPA1
|
9.68 |
11 |
| 44. |
Aluminum
|
Neoplasm Invasiveness
|
|
|
18 genes: ACO1 | AMBP | CAT | CDH1 | CTSS | CXCL12 | EPOR | GAB2 | HIF1A | IGF1 | MAPK3 | MMP1 | MMP2 | MMP9 | SNAI1 | SOD2 | TF | TNF
|
9.65 |
20 |
| 45. |
Aluminum
|
Neoplasm Metastasis
|
|
|
25 genes: ACE | AGTR1 | ALK | ARHGDIA | CAT | CDH1 | EHMT2 | EPOR | ESR1 | GAB2 | IGF1 | IL18 | IL2 | MAPK3 | MMP1 | MMP2 | MMP9 | OSM | PDE5A | PROX1 | PTGS2 | SNAI1 | SOD2 | TNF | TNFSF10
|
9.51 |
27 |
| 46. |
Aluminum
|
Prostatic Neoplasms
|
|
|
43 genes: ACE | ACHE | ACSL4 | AR | BAX | BCAS1 | BGLAP | CDH1 | CRYAB | CXCL12 | CYP7B1 | ERBB3 | ESR1 | FASLG | FOXP4 | HIF1A | HIP1 | HSD3B1 | HSD3B2 | ID3 | IGF1 | IL18 | IL2 | KLF6 | LAMB2 | MBD2 | MED12 | MME | MMP9 | MSR1 | MUC4 | MYH14 | NAT1 | NGFR | PTGS2 | PTHLH | SEPP1 | SOD2 | TIRAP | TNFSF10 | TPD52L1 | USO1 | VDR
|
9.34 |
59 |
| 47. |
Aluminum
|
Edema
|
|
|
4 genes: CASP3 | CAT | PTGS2 | TNF
|
9.31 |
2 |
| 48. |
Aluminum
|
SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE, B CELL-POSITIVE, NK CELL-POSITIVE
|
|
|
3 genes: CD3D | CD3E | PTPRC
|
9.18 |
1 |
| 49. |
fluoroaluminum
|
Neoplasm Invasiveness
|
|
|
2 genes: BCAR1 | PTK2
|
9.16 |
2 |
| 50. |
Aluminum
|
Tachycardia
|
|
|
3 genes: DRD2 | GNRH1 | TNF
|
9.13 |
4 |
Illuminating how chemicals affect human health.
Aluminum