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Chemical Aluminum

These diseases are associated with Aluminum or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 1,301 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Aluminum Alzheimer Disease M
22 genes: ABCA7 | ACE | ACHE | APP | BAX | CASP3 | ESR1 | F2 | HMOX1 | IDE | IGF1 | IL1B | MAPT | MPO | NPY | PICALM | PYY | SLC30A4 | SOD2 | TF | TNF | TREM2
15.38 56
2. Aluminum Poisoning M
3 genes: ACHE | ALB | SLC22A2
7.17 8
3. Aluminum Nerve Degeneration M
25 genes: AGTPBP1 | APP | ATXN3 | BAX | CASP3 | CDH1 | CNTF | EPOR | F2 | GST-1 | IGF1 | KCNJ6 | MAPK3 | NGFR | NOS1 | OTX2 | SEPP1 | SKN-1 | SLC1A2 | SLC6A3 | SMF-3 | SNCA | SOD2 | TNF | XDH
7.04 39
4. Aluminum Lung Diseases M
14 genes: ACE | CLEC4E | HIF1A | IL13 | IRX1 | IRX2 | IRX3 | KIT | MPO | PTGS2 | PTH1R | PTHLH | SCGB1A1 | TNF
6.85 11
5. Aluminum Neurodegenerative Diseases M
10 genes: APOD | APP | CRYAB | GSR | HMOX1 | MAPT | NGFR | SEPP1 | SNCA | SOD2
5.89 12
6. Aluminum Amyotrophic Lateral Sclerosis M
6 genes: GFAP | GSR | PLA2G4A | PTGS2 | SLC1A2 | UNC13A
5.58 6
7. Aluminum Brain Diseases M
2 genes: ALB | APP
5.40 5
8. Aluminum Cognition Disorders M
4 genes: APP | DRD2 | PTGS2 | SLC4A10
4.38 7
9. Aluminum Dyslipidemias M   1 gene: APOB 3.73 2
10. Aluminum Memory Disorders M
6 genes: ACHE | APP | IL1B | MAPT | NPY | SLC6A3
3.32 13
11. Aluminum Neurotoxicity Syndromes M
4 genes: ALOX5AP | CASP3 | CD3D | RNASE6
3.26 3
12. Aluminum Fragile X Syndrome M   1 gene: APP 3.14 2
13. Aluminum Bronchial Hyperreactivity M
2 genes: IL13 | TRPA1
3.00 4
14. Aluminum Anemia M
7 genes: GSR | IFNA2 | IL2 | IL3 | PTH | SOD2 | TNF
2.64 14
15. Aluminum Inflammation M
19 genes: ADIPOQ | BDKRB2 | CD3E | CXCL8 | EFNB1 | HMOX1 | IL1B | LTF | MPO | NOS2 | PTGS2 | SCGB1A1 | SLC22A5 | TF | TFRC | TLR2 | TNF | TRPA1 | ZFP36
2.44 39
16. Aluminum Neoplasms M
12 genes: ATF2 | CAT | GLP1R | IL18 | IL1B | IL2 | KDM6A | LTF | NAT1 | PTGS2 | SOD2 | VDR
2.37 18
17. Aluminum Parkinson Disease M
9 genes: DRD2 | GFAP | GPX1 | HMOX1 | MAPT | SLC6A3 | SNCA | SOD2 | TNF
2.19 32
18. Aluminum Nervous System Diseases M
12 genes: ACHE | CASP3 | EN1 | GFAP | ID3 | NFATC2 | NOS1 | PTGS2 | SEPP1 | SLC19A1 | SLC6A3 | TNF
2.15 16
19. Aluminum Diabetes Complications M     1
20. Aluminum Epilepsy, Tonic-Clonic M     1
21. Aluminum Eye Diseases M     1
22. Aluminum Granuloma M     1
23. Aluminum Heavy Metal Toxicity M     1
24. Aluminum Lymphadenitis M     1
25. Aluminum Multiple Sclerosis, Chronic Progressive M     1
26. Aluminum Multiple Sclerosis, Relapsing-Remitting M     1
27. Aluminum Osteomalacia M     1
28. Aluminum Renal Osteodystrophy M     1
29. Aluminum Autistic Disorder  
37 genes: ADM | AR | CACNA1H | CAT | GPX1 | HDLBP | HOXD11 | HTR1B | HTR1D | HTR5A | IGF1 | IL13 | IL15 | IL2 | IL4 | IL5 | LASP1 | MAGEL2 | MEF2C | NF1 | NOS2 | NRXN1 | PDE4B | PECAM1 | PIK3CG | PLA2G4A | PRKCB | PTGS2 | ROBO2 | SHANK2 | SLC19A1 | SLC1A3 | SLC6A8 | TDO2 | TF | TNFRSF1B | XDH
22.03 39
30. Aluminum Obesity  
30 genes: ACLY | ADH1B | ADIPOQ | ADRB1 | AKAP1 | CES1 | CPB2 | CTF1 | CTSS | EFNB1 | ESR1 | F2 | GNPDA2 | GPX1 | HMOX1 | HOXB5 | MMP9 | NHLH2 | NPY5R | PACS1 | PCSK1 | PTGS2 | PYY | SIM1 | SOD2 | TF | TFRC | TNF | TNFRSF1B | UCP1
20.05 30
31. Aluminum Endometriosis  
21 genes: C10ORF10 | CD226 | CNIH3 | IGF1 | IL15 | IL1R1 | ITGA2 | LTF | MED16 | NEFM | NR3C2 | NR4A1 | OSR2 | PAPPA | PGR | PLXNC1 | RASL11A | RORB | RXFP1 | SEPP1 | THRA
14.28 4
32. Aluminum Colorectal Neoplasms  
30 genes: ABCA1 | ABCA10 | ABCA8 | ADH1B | BRAF | CD226 | CDH1 | COL7A1 | CXCL8 | EP300 | FLCN | GRID1 | IFNA1 | IFNA2 | MMP1 | MMP2 | NAMPT | PRKCB | PRKCE | PTGS2 | PYCARD | SEPP1 | SFRP5 | SLC19A1 | SOD2 | TFRC | TGFBR1 | TLR2 | TNF | TNFSF10
14.20 33
33. Aluminum Peripheral Nervous System Diseases  
41 genes: ABCA1 | AICDA | ALDH1A1 | APOB | ARSA | BAX | CEP250 | CES1 | DBH | ESR1 | FMO3 | GFAP | GPR15 | GPX1 | GZMH | ID3 | IFNA1 | IGF1 | IL18 | IL2 | IL3 | JUN | MN1 | MTR | NAT1 | NEFH | NEK4 | NPY | PIK3CG | PLXDC2 | PRKCE | PTGIS | SIM1 | SLC22A5 | SLC22A8 | SOD2 | TLN2 | TNF | TNFSF8 | UCP1 | WNT11
14.16 7
34. Aluminum Arthritis, Rheumatoid  
23 genes: ADIPOQ | BAIAP2L1 | BDKRB2 | BLK | CAT | CD3E | CD5 | CXCL6 | HOXD11 | HOXD13 | IL18 | IL1B | MMP2 | MPO | POU3F1 | PRDM1 | PTGS2 | PTPN22 | PTPRC | RGMB | SOD2 | TAGAP | TNF
13.52 15
35. Aluminum Prostatic Neoplasms  
47 genes: ACE | ACHE | ACSL4 | AR | BAX | BCAS1 | BGLAP | CDH1 | CRYAB | CXCL12 | CXCL8 | CYP7B1 | ERBB3 | ESR1 | FASLG | FOXP4 | HIF1A | HIP1 | HSD3B1 | HSD3B2 | ID3 | IGF1 | IL18 | IL2 | KLF6 | LAMB2 | MBD2 | MED12 | MME | MMP9 | MSR1 | MUC4 | MYH14 | NAT1 | NGFR | OLFM1 | PRRX1 | PTGS2 | PTHLH | SEPP1 | SOD2 | TIRAP | TMF1 | TNFSF10 | TPD52L1 | USO1 | VDR
13.39 62
36. Aluminum Breast Neoplasms  
52 genes: ACHE | AFP | APOBEC3A | AR | ARHGDIA | BAX | BCL2A1 | C10ORF10 | CD74 | CDH1 | CLUL1 | COL7A1 | CUL5 | CXCL12 | CXCL8 | EPOR | ESR1 | FOXP3 | GPX1 | HEYL | HIF1A | HMOX1 | HNRNPR | HOXD11 | IGF1 | IL1B | JUN | KIT | MAL | MECOM | MME | MMP1 | MMP2 | MMP9 | MTR | NMBR | NOS2 | PGR | PLA2G4A | PTGS2 | PTHLH | RAD51B | RIBC2 | SFRP5 | SIM1 | SLC2A1 | SNAI1 | SOD2 | TFRC | TNF | TNFSF10 | WWOX
12.26 62
37. fluoroaluminum Adrenocortical Carcinoma  
2 genes: ABCB1 | IGF2
12.06 3
38. Aluminum Nausea  
2 genes: IFNA2 | TNF
11.87 4
39. fluoroaluminum Carcinoma, Hepatocellular  
3 genes: ABCB1 | IGF2 | PTK2
11.69 4
40. Aluminum Radiation Injuries, Experimental  
6 genes: IL18 | IL1B | MAPK3 | NOS1 | SOD2 | TNF
11.66 3
41. Aluminum Vomiting  
2 genes: GNRH1 | IFNA2
11.13 3
42. Aluminum Amphetamine-Related Disorders  
16 genes: ACHE | DRD1A | DRD2 | GABRG2 | HTR1B | MAP2K5 | MARC1 | NOS1 | OPRM1 | PDE4B | POU5F1 | PRKG1 | PSD3 | RAPGEF5 | SLC6A3 | SNCA
10.76 12
43. Aluminum Headache  
2 genes: GNRH1 | IFNA2
10.70 2
44. Aluminum Calcinosis  
10 genes: AHSG | BGLAP | C6 | CASP3 | IL18 | IL1B | LY86 | MMP2 | MMP9 | PYCARD
10.61 4
45. Aluminum Catalepsy  
2 genes: DRD1A | DRD2
10.33 4
46. Aluminum Necrosis  
8 genes: APP | ATG7 | CAT | CTF1 | IL1B | NOS2 | SOD2 | TNF
10.29 11
47. Aluminum Neoplasm Metastasis  
26 genes: ACE | AGTR1 | ALK | ARHGDIA | CAT | CDH1 | CXCL12 | EHMT2 | EPOR | ESR1 | GAB2 | IGF1 | IL18 | IL2 | MAPK3 | MMP1 | MMP2 | MMP9 | OSM | PDE5A | PROX1 | PTGS2 | SNAI1 | SOD2 | TNF | TNFSF10
10.13 34
48. Aluminum Brain Injuries  
19 genes: ALB | CES1 | CHRM2 | CLEC4E | IL12RB2 | IL13RA2 | IL1B | IL1R1 | IL2 | JUN | LY86 | MMP9 | MPO | PGLYRP1 | PTGS2 | S100B | TLR2 | TNF | TNFSF10
10.09 10
49. Aluminum Liver Cirrhosis, Experimental  
22 genes: ACHE | ADIPOQ | ADM | AFP | ALB | ALDH1A1 | HMOX1 | IFNA1 | IFNA2 | IGF1 | IL1B | MGAT5 | MME | MMP1 | MMP2 | MMP9 | NOS2 | OSM | PTGS2 | SPIN2A | TNF | TRF
10.02 24
50. Aluminum Brain Ischemia  
18 genes: ACE | ALB | CASP3 | CAT | F2 | GPX1 | HIF1A | IL18 | IL1B | JUN | MAPK3 | MMP9 | MPO | NOS2 | PTGS2 | SOD2 | TNF | TNFRSF1B
9.88 16
1–50 of 1,301 results.