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Chemical Aluminum

These diseases are associated with Aluminum or its descendants. Each association is curated (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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1–50 of 1,284 results.
  Chemical Disease Direct Evidence Enrichment Analysis Inference Network Inference Score References
1. Aluminum Alzheimer Disease M
22 genes: ABCA7 | ACE | ACHE | APP | BAX | CASP3 | ESR1 | F2 | HMOX1 | IDE | IGF1 | IL1B | MAPT | MPO | NPY | PICALM | PYY | SLC30A4 | SOD2 | TF | TNF | TREM2
14.66 56
2. Aluminum Poisoning M
3 genes: ACHE | ALB | SLC22A2
7.63 8
3. Aluminum Lung Diseases M
14 genes: ACE | CLEC4E | HIF1A | IL13 | IRX1 | IRX2 | IRX3 | KIT | MPO | PTGS2 | PTH1R | PTHLH | SCGB1A1 | TNF
6.54 11
4. Aluminum Nerve Degeneration M
25 genes: AGTPBP1 | APP | ATXN3 | BAX | CASP3 | CDH1 | CNTF | EPOR | F2 | GST-1 | IGF1 | KCNJ6 | MAPK3 | NGFR | NOS1 | OTX2 | SEPP1 | SKN-1 | SLC1A2 | SLC6A3 | SMF-3 | SNCA | SOD2 | TNF | XDH
6.46 38
5. Aluminum Brain Diseases M
2 genes: ALB | APP
5.64 5
6. Aluminum Neurodegenerative Diseases M
9 genes: APOD | APP | CRYAB | HMOX1 | MAPT | NGFR | SEPP1 | SNCA | SOD2
4.64 12
7. Aluminum Amyotrophic Lateral Sclerosis M
5 genes: GFAP | PLA2G4A | PTGS2 | SLC1A2 | UNC13A
4.11 5
8. Aluminum Dyslipidemias M   1 gene: APOB 3.79 2
9. Aluminum Memory Disorders M
6 genes: ACHE | APP | IL1B | MAPT | NPY | SLC6A3
3.62 12
10. Aluminum Neurotoxicity Syndromes M
4 genes: ALOX5AP | CASP3 | CD3D | RNASE6
3.47 3
11. Aluminum Anemia M
6 genes: IFNA2 | IL2 | IL3 | PTH | SOD2 | TNF
3.38 13
12. Aluminum Fragile X Syndrome M   1 gene: APP 3.10 2
13. Aluminum Bronchial Hyperreactivity M
2 genes: IL13 | TRPA1
3.00 4
14. Aluminum Inflammation M
17 genes: ADIPOQ | BDKRB2 | EFNB1 | HMOX1 | IL1B | LTF | MPO | NOS2 | PTGS2 | SCGB1A1 | SLC22A5 | TF | TFRC | TLR2 | TNF | TRPA1 | ZFP36
2.79 37
15. Aluminum Neoplasms M
11 genes: ATF2 | CAT | GLP1R | IL18 | IL2 | KDM6A | LTF | NAT1 | PTGS2 | SOD2 | VDR
2.68 17
16. Aluminum Nervous System Diseases M
12 genes: ACHE | CASP3 | EN1 | GFAP | ID3 | NFATC2 | NOS1 | PTGS2 | SEPP1 | SLC19A1 | SLC6A3 | TNF
2.17 16
17. Aluminum Parkinson Disease M
9 genes: DRD2 | GFAP | GPX1 | HMOX1 | MAPT | SLC6A3 | SNCA | SOD2 | TNF
2.11 32
18. Aluminum Diabetes Complications M     1
19. Aluminum Epilepsy, Tonic-Clonic M     1
20. Aluminum Eye Diseases M     1
21. Aluminum Granuloma M     1
22. Aluminum Heavy Metal Toxicity M     1
23. Aluminum Lymphadenitis M     1
24. Aluminum Multiple Sclerosis, Chronic Progressive M     1
25. Aluminum Multiple Sclerosis, Relapsing-Remitting M     1
26. Aluminum Osteomalacia M     1
27. Aluminum Renal Osteodystrophy M     1
28. Aluminum Autistic Disorder  
37 genes: ADM | AR | CACNA1H | CAT | GPX1 | HDLBP | HOXD11 | HTR1B | HTR1D | HTR5A | IGF1 | IL13 | IL15 | IL2 | IL4 | IL5 | LASP1 | MAGEL2 | MEF2C | NF1 | NOS2 | NRXN1 | PDE4B | PECAM1 | PIK3CG | PLA2G4A | PRKCB | PTGS2 | ROBO2 | SHANK2 | SLC19A1 | SLC1A3 | SLC6A8 | TDO2 | TF | TNFRSF1B | XDH
20.72 39
29. Aluminum Obesity  
30 genes: ACLY | ADH1B | ADIPOQ | ADRB1 | AKAP1 | CES1 | CPB2 | CTF1 | CTSS | EFNB1 | ESR1 | F2 | GNPDA2 | GPX1 | HMOX1 | HOXB5 | MMP9 | NHLH2 | NPY5R | PACS1 | PCSK1 | PTGS2 | PYY | SIM1 | SOD2 | TF | TFRC | TNF | TNFRSF1B | UCP1
19.00 30
30. Aluminum Endometriosis  
21 genes: C10ORF10 | CD226 | CNIH3 | IGF1 | IL15 | IL1R1 | ITGA2 | LTF | MED16 | NEFM | NR3C2 | NR4A1 | OSR2 | PAPPA | PGR | PLXNC1 | RASL11A | RORB | RXFP1 | SEPP1 | THRA
13.43 4
31. Aluminum Peripheral Nervous System Diseases  
41 genes: ABCA1 | AICDA | ALDH1A1 | APOB | ARSA | BAX | CEP250 | CES1 | DBH | ESR1 | FMO3 | GFAP | GPR15 | GPX1 | GZMH | ID3 | IFNA1 | IGF1 | IL18 | IL2 | IL3 | JUN | MN1 | MTR | NAT1 | NEFH | NEK4 | NPY | PIK3CG | PLXDC2 | PRKCE | PTGIS | SIM1 | SLC22A5 | SLC22A8 | SOD2 | TLN2 | TNF | TNFSF8 | UCP1 | WNT11
12.85 7
32. Aluminum Arthritis, Rheumatoid  
23 genes: ADIPOQ | BAIAP2L1 | BDKRB2 | BLK | CAT | CD3E | CD5 | CXCL6 | HOXD11 | HOXD13 | IL18 | IL1B | MMP2 | MPO | POU3F1 | PRDM1 | PTGS2 | PTPN22 | PTPRC | RGMB | SOD2 | TAGAP | TNF
12.71 15
33. Aluminum Nausea  
2 genes: IFNA2 | TNF
12.58 4
34. fluoroaluminum Adrenocortical Carcinoma  
2 genes: ABCB1 | IGF2
12.57 3
35. Aluminum Vomiting  
2 genes: GNRH1 | IFNA2
11.76 3
36. fluoroaluminum Carcinoma, Hepatocellular  
3 genes: ABCB1 | IGF2 | PTK2
11.56 4
37. Aluminum Colorectal Neoplasms  
26 genes: ADH1B | BRAF | CD226 | CDH1 | COL7A1 | EP300 | FLCN | GRID1 | IFNA1 | IFNA2 | MMP1 | MMP2 | NAMPT | PRKCB | PRKCE | PTGS2 | PYCARD | SEPP1 | SFRP5 | SLC19A1 | SOD2 | TFRC | TGFBR1 | TLR2 | TNF | TNFSF10
11.50 31
38. Aluminum Prostatic Neoplasms  
46 genes: ACE | ACHE | ACSL4 | AR | BAX | BCAS1 | BGLAP | CDH1 | CRYAB | CXCL12 | CYP7B1 | ERBB3 | ESR1 | FASLG | FOXP4 | HIF1A | HIP1 | HSD3B1 | HSD3B2 | ID3 | IGF1 | IL18 | IL2 | KLF6 | LAMB2 | MBD2 | MED12 | MME | MMP9 | MSR1 | MUC4 | MYH14 | NAT1 | NGFR | OLFM1 | PRRX1 | PTGS2 | PTHLH | SEPP1 | SOD2 | TIRAP | TMF1 | TNFSF10 | TPD52L1 | USO1 | VDR
11.39 61
39. Aluminum Radiation Injuries, Experimental  
6 genes: IL18 | IL1B | MAPK3 | NOS1 | SOD2 | TNF
11.34 3
40. Aluminum Headache  
2 genes: GNRH1 | IFNA2
11.33 2
41. Aluminum Seizures  
18 genes: ACHE | ALAD | CAT | CHAT | DRD1A | DRD2 | GRIK1 | HTR1B | IL1B | NGFR | NOS1 | NOS2 | NPY | OPRM1 | PTGS2 | SLC2A1 | SLC8A3 | SOD2
11.19 26
42. Aluminum Necrosis  
8 genes: APP | ATG7 | CAT | CTF1 | IL1B | NOS2 | SOD2 | TNF
11.02 11
43. Aluminum Catalepsy  
2 genes: DRD1A | DRD2
10.94 4
44. Aluminum Calcinosis  
10 genes: AHSG | BGLAP | C6 | CASP3 | IL18 | IL1B | LY86 | MMP2 | MMP9 | PYCARD
10.61 4
45. Aluminum Bradycardia  
4 genes: CHRM2 | DRD2 | GNAI2 | GNRH1
10.25 5
46. Aluminum Amphetamine-Related Disorders  
16 genes: ACHE | DRD1A | DRD2 | GABRG2 | HTR1B | MAP2K5 | MARC1 | NOS1 | OPRM1 | PDE4B | POU5F1 | PRKG1 | PSD3 | RAPGEF5 | SLC6A3 | SNCA
10.12 12
47. Aluminum Edema  
4 genes: CASP3 | CAT | PTGS2 | TNF
9.62 2
48. Aluminum Neoplasm Metastasis  
26 genes: ACE | AGTR1 | ALK | ARHGDIA | CAT | CDH1 | CXCL12 | EHMT2 | EPOR | ESR1 | GAB2 | IGF1 | IL18 | IL2 | MAPK3 | MMP1 | MMP2 | MMP9 | OSM | PDE5A | PROX1 | PTGS2 | SNAI1 | SOD2 | TNF | TNFSF10
9.57 33
49. Aluminum Brain Injuries  
19 genes: ALB | CES1 | CHRM2 | CLEC4E | IL12RB2 | IL13RA2 | IL1B | IL1R1 | IL2 | JUN | LY86 | MMP9 | MPO | PGLYRP1 | PTGS2 | S100B | TLR2 | TNF | TNFSF10
9.39 10
50. Aluminum SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE, B CELL-POSITIVE, NK CELL-POSITIVE  
3 genes: CD3D | CD3E | PTPRC
9.29 1
1–50 of 1,284 results.