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Help: Diseases


  1. Overview
  2. Basics
  3. Hierarchies
  4. Footnotes


CTD's MEDIC disease vocabulary is a modified subset of descriptors from the “Diseases” [C] branch of the U.S. National Library of Medicine's Medical Subject Headings (MeSH®), combined with genetic disorders from the Online Mendelian Inheritance in Man® (OMIM®) database. MeSH is a hierarchical vocabulary used to index articles for MEDLINE®/PubMed®.[1] OMIM contains textual information, references related to diseases, links to MEDLINE and sequence records in the Entrez system, and links to additional related resources at NCBI. It is developed at the Johns Hopkins University.

MEDIC is structured as a polyhierarchic tree in which a term may appear as a node in more than one branch. A disease may have different descendants in each branch in which it appears (although CTD combines all descendants from all branches to reflect how our data is curated, searched, and displayed).

OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.

Top ↑ Basics


The name of the disease.


Synonyms of the disease.

Categories (MEDIC-Slim)

MEDIC-Slim is a set of terms, derived from the MeSH tree structure for the “Diseases” [C] branch, that classifies MEDIC diseases into high-level categories. MEDIC-Slim allows similar diseases to be grouped for better analysis and visualization.

The mapping of MEDIC diseases to their MEDIC-Slim classification terms was accomplished computationally by collapsing terms upward in the hierarchy until resolving to one or more slim terms.


Unique identifier(s) assigned to the disease by MeSH and/or OMIM, linked to the source record(s) for the disease. The primary ID is shown in bold.

Curator Notes

Comments added by a CTD curator.

Use Term in Query

If you arrived at this page from a query form, you may click the Use button to add this term to the Disease field on the query form.

Top ↑ Hierarchies

Each disease occurs in at least one location of the hierarchy; many occur in more than one. Each ancestor path of the hierarchy is presented separately, but descendants for all paths are aggregated in a single display to reflect how data in CTD is curated, searched, and displayed.

Nodes are indented to indicate their relative level in the tree. A node marked by the + symbol has descendants in at least one of the hierarchical paths displayed on the current page. The same term may or may not have descendants, depending on each particular path in which it appears. Click a term in the ancestor path to move up the tree, or click a descendant node to move down.

If you arrived at this page from a query form, you may click the Use button to add a disease node to the Disease field on the query form. Searching by node (rather than by the disease name) will yield only those items related to nodes in a particular tree.

Top ↑ Footnotes

Lipscomb CE. Medical Subject Headings (MeSH). Bull Med Libr Assoc. 2000 Jul;88(3):265-6. PMID:10928714