Acknowledgments
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Scientific Resources
We acknowledge these valuable scientific resources related to CTD's mission.
- BIAdb
- A database for Benzylisoquinoline Alkaloids.
- BioGraph
- Biomedical knowledge discovery server.
- BioGRID
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The Biological General Repository for Interaction Datasets: An online interaction repository with data compiled through comprehensive curation efforts.
- BioXM™
- A fully customizable knowledge management solution for better integrated and knowledge-based drug discovery and development.
- Bisphenol A Genomics Data Portal
- A database of genomics datasets related to health effects of Bisphenol A exposure.
- CancerResource
- Explores the drug target interaction space for applying personalized medicine.
- CCRIS
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Chemical Carcinogenesis Research Information System: A factual database sponsored by the National Cancer Institute. It contains evaluated data and information derived from both short- and long-term bioassays on over 8,000 chemicals. Studies relate to carcinogens, mutagens, tumor promoters, cocarcinogens, metabolites, and inhibitors of carcinogens.
- chem2bio2rdf
- A semantic framework for linking and data mining chemogenomic and systems chemical biology data.
- ChemIDplus®
- A resource providing access to structure and nomenclature information for the identification of chemical substances cited in NLM® databases.
- ChemProt
- Annotated and predicted chemical-protein interactions.
- ChemSpider
- Links together compound information across the web, providing free text and structure search access of millions of chemical structures.
- DrugBank
- A resource that combines detailed drug (i.e., chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e., sequence, structure, and pathway) information.
- GAD
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Genetic Association Database: An archive of human genetic association studies of complex diseases and disorders. GAD's goal is to allow the user to identify medically relevant polymorphisms from the large volume of polymorphism and mutational data, in the context of standardized nomenclature.
- Ganfyd
- Get a Note from Your Doctor: a collaborative medical reference wiki by medical professionals and invited non-medical experts.
- GENE-TOX
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Genetic Toxicology Data Bank: A database created by the US Environmental Protection Agency with genetic toxicology test results on thousands of chemicals. In the field of genetic toxicology, selected mutagenicity assay systems and the source literature are reviewed by work panels of scientific experts for each of the test systems under evaluation, and the GENE-TOX data bank is the product of these data review activities.
- GO
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Gene Ontology Consortium: Provides a controlled vocabulary of terms for describing gene product characteristics and gene product annotation data from GO Consortium members, as well as tools to access and process this data.
- HSDB®
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Hazardous Substances Data Bank: A comprehensive, scientifically reviewed, factual database containing records for toxic or potentially toxic chemicals. It contains extensive information in such areas as toxicity, environmental fate, human exposure, chemical safety, waste disposal, emergency handling, and regulatory requirements.
- KEGG
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Kyoto Encyclopedia of Genes and Genomes: A collection of manually drawn pathway maps representing knowledge of the molecular interaction and reaction networks. These data are integrated with chemicals, genes and diseases in CTD to provide insights into molecular networks that may be affected by chemicals, and possible mechanisms underlying environmental diseases.
- MeSH®
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NLM® Medical Subject Headings®: The National Library of Medicine®'s hierarchical controlled vocabulary thesaurus. Components of this vocabulary are used for the CTD chemical and disease vocabularies.
- MIRIAM Registry
- This application enables users to search collections of curated models with precision, quickly identify the biological phenomena that a given curated model or model constituent represents, and facilitates model reuse, model composition into large subcellular models, and format conversion.
- NCBI
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National Center for Biotechnology Information: A division of the National Library of Medicine (NLM) and is a component of the National Institutes of Health (NIH). CTD incorporates information from NCBI resources including the Entrez Gene database, PubChem, and OMIM.
- OMIM®
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Online Mendelian Inheritance in Man®: A catalog of human genes and genetic disorders. OMIM data and disease terms are integrated into CTD to provide disease information associated with chemicals and genes.
- PharmGKB
- Curates information that establishes knowledge about the relationships among drugs, diseases, and genes, including their variations and gene products.
- PhenoHM
- Human-Mouse Comparative Phenomics Server.
- PPDB
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Pathogenic Pathway Database for Periodontitis: A manual collection of pathogenic pathways for periodontitis.
- PubChem
- Provides information on the biological activities of small molecules.
- RefGene
- Indexes of genes and antibodies.
- STITCH
- A resource to explore known and predicted interactions of chemicals and proteins. Chemicals are linked to other chemicals and proteins by evidence derived from experiments, databases, and the literature.
- T3DB
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Toxin and Toxin Target Database: A resource that combines detailed toxin data with comprehensive toxin target information.
- ToppGene
- A portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network.
- TOXLINE®
- A bibliographic database covering the biochemical, pharmacological, physiological, and toxicological effects of drugs and other chemicals.
- UCSC Genome Browser
- Contains the reference sequence and working draft assemblies for a large collection of genomes. It also provides a portal to the ENCODE project.
- UniProt
- A comprehensive catalog of information on proteins. It is a central repository of protein sequence and function created by joining the information contained in UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and PIR.
- WENDI
- A tool for finding non-obvious associations between compounds and biology.
- WhichGenes
- A tool for building gene sets to use for further experiments.
CTD thanks the contributors to all the open-source software on which we rely.
CTD also appreciates Balsamiq's kind donation of “do-gooder” licenses
for its excellent Mockups and Mockups Confluence Plugin products.
Illuminating how chemicals affect human health.